About   Help   FAQ
Tg(Mylpf-cre)3Kraj - Nervous System
Recombinase Activity Detail
Allele Information
Allele:
Tg(Mylpf-cre)3Kraj
transgene insertion 3, Stan Krajewski 		Driver: Mylpf
Type: Transgenic (Cre/Flp)
Synonym: MLCcreI, MLC2v-CRE3, CRE3
Molecular description: A 250-bp fragment of the rat ventricular light chain II gene (Mylpf) was used as promoter to drive expression of the cre recombinase cDNA. The construct also carries an additional generic intron derived from the PMLCSV0A.GI placed between the promoter and the cre cDNA. Crosses of these mice were made to mice (dh4) carrying a transgenic reporter gene (a dominant-hygR gene separated from a constitutive PGK promoter by a loxP-flanked PGK-neo cassette; cre recombination results in generation of the active-hygR allele detected by PCR). Line 3 was determined to express cre selectively in the brain.
Find mice (IMSR): Mouse Strains: 0 lines available       Cell Lines: 0 lines available
Additional Tissues: Tg(Mylpf-cre)3Kraj activity also observed in:
sensory organs
Tissue Information
Nervous System Other recombinase alleles with activity in Nervous System tissues:
Images
Drag images to compare to others or to data in the table below. Drag corners to resize images for more detail. Reset Images
J:99342
Fig. 2 J:99342
Fig. 3.1 J:99342
Fig. 3.2 J:99342
Fig. 3.3 J:99342
Fig. 3.4
Recombinase Activity
Click heading to resort table.
Assays Genotypic Background Result Notes  
References
All for this allele: 4 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support. 		last database update
05/08/2013
MGI 5.13 		The Jackson Laboratory