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Foxn1tm3(cre)Nrm - Hemolymphoid System
Recombinase Activity Detail
Allele Information
Allele:
Foxn1tm3(cre)Nrm
forkhead box N1; targeted mutation 3, Nancy R Manley
Driver: Foxn1
Type: Targeted (Recombinase)
Synonym: Foxn1ex9cre
Molecular description: An IRES-cre and floxed or frt neo cassette were inserted into the 3' end of exon 9. Insertion was confirmed by PCR of genomic DNA. Cre activity was tested by a cross with R26R mice. Removal of the neo cassette by frt-mediated recombination following a cross with Tg(ACTFLPe)9205Dym mice results in a loss of ectopic cre expression but specific expression is retained. RT-PCR was used to confirm that endogenous gene expression was unaffected.
Find mice (IMSR): Mouse Strains: 1 strain available       Cell Lines: 0 lines available
Additional Tissues: Foxn1tm3(cre)Nrm activity also observed in:
branchial arches
Tissue Information
Hemolymphoid System Other recombinase alleles with activity in Hemolymphoid System tissues:
Images
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J:125817 Fig. 2 J:125817 Fig. 4
Recombinase Activity
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Assays Genotypic Background Result Notes  
References
All for this allele: 12 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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Funding Information
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last database update
08/19/2014
MGI 5.19
The Jackson Laboratory