About   Help   FAQ
Tg(dlx6a-cre)1Mekk - Nervous System
Recombinase Activity Detail
Allele Information
transgene insertion 1, Marc Ekker
Driver: dlx6a
Type: Transgenic (Recombinase)
Synonym: Dlx5/6-Cre, Dlx5/6i-Cre, line 8561, Tg(dlx6a-cre)1Mars
Molecular description: A cre gene was placed under the control of the I56i and I56ii enhancer elements of zebrafish dlx5a and a 3.5kb genomic DNA fragment flanking the 5' region of the zebrafish dlx6a open reading frame and containing the 5'UTR. The dlx6a flanking region on its own cannot produce tissue specific expression but increases the activity of the enhancers to produce expression that recapitulate endogenous Dlx5 expression. Tissue specific expression was confirmed by test crosses to reporter mice strains, including Tg(ACTB-Bgeo/ALPP)1Lbe, Tg(ACTB-Bgeo/GFP)21Lbe and Gt(ROSA)26Sortm1Sor.
Find mice (IMSR): Mouse Strains: 2 strains available       Cell Lines: 0 lines available
Additional Tissues: Tg(dlx6a-cre)1Mekk activity also observed in:
Tissue Information
Nervous System Other recombinase alleles with activity in Nervous System tissues:
Drag images to compare to others or to data in the table below. Drag corners to resize images for more detail. Reset Images
J:193672 Full image
Fig. dlx Brain P56
J:193672 Full image
Fig. dlx Brain P7
J:193672 Full image
Fig. dlx Embryo 2 E10.5
J:193672 Full image
Fig. dlx Embryo 3 E10.5
J:193672 Full image
Fig. dlx Sp Cord P56
J:193672 Full image
Fig. dlx Sp Cord P7
Recombinase Activity
Click heading to re-sort table.
Assays Genotypic Background Result Notes  
All for this allele: 48 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
MGI 6.03
The Jackson Laboratory