Tg(Aqp2-cre)1Dek - Liver & Biliary System Recombinase Activity Detail MGI Mouse

Tg(Aqp2-cre)1Dek - Liver & Biliary System
Recombinase Activity Detail

Allele Information | Recombinase Activity | References

Allele Information

Allele:

Tg(Aqp2-cre)1Dek
transgene insertion 1, Donald E Kohan

Driver: Aqp2
Type: Transgenic (Recombinase)

Synonym:

AQP2-Cre

Molecular description:

This transgene contains a 9.5 kb fragment of the mouse aquaporin 2 gene 5'-flanking region placed upstream of a Cre recombinase sequence (with SV40 nuclear localization signal at the amino terminus and an 11-amino acid epitope tag derived from Herpes simplex virus glycoprotein D located at the carboxy terminus). The aquaporin regulatory sequences drive Cre expression in the collecting ducts of the kidney and in sperm.

Find mice (IMSR):

Mouse Strains: 1 strain available Cell Lines: 0 lines available

Additional Tissues:

Tg(Aqp2-cre)1Dek activity also observed in:
head, nervous system, renal & urinary system, reproductive system

Recombinase Activity

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Assays Genotypic Background Result Notes

References

All for this allele:

30 reference(s)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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