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Allele Information
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Allele:
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Tg(Sim1-cre)1Lowl
transgene insertion 1, Bradford B Lowell
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Driver: Sim1
Type: Transgenic (Cre/Flp)
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Synonym:
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Sim1-Cre
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Molecular description:
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The cre ATG was inserted via recombineering techniques, into the Sim1 ATG site of a BAC containing 137.1 kb of genomic C57BL/6 Sim1 sequences up to and including exon 8. The inserted cre sequence deleted the first 31 bp of the Sim1 gene.
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Find mice (IMSR):
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Mouse Strains:
2 lines available
Cell Lines:
0 lines available
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Additional Tissues:
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Tg(Sim1-cre)1Lowl activity also observed in:
adipose tissue,
alimentary system,
branchial arches,
cardiovascular system,
cavities and their linings,
endocrine system,
hemolymphoid system,
integumental system,
limbs,
liver and biliary system,
mesenchyme,
muscle,
nervous system,
renal and urinary system,
respiratory system,
sensory organs,
skeletal system,
tail
(less)
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Tissue Information
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Reproductive System
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Other recombinase alleles with activity in Reproductive System tissues:
Alpltm1(cre)Nagy,
Amhr2tm3(cre)Bhr,
Calb2tm1(cre)Zjh,
Ccktm1.1(cre)Zjh,
Cdkn2atm3(cre)Cjs,
Chattm1(cre)Lowl,
Corttm1(cre)Zjh,
Crhtm1(cre)Zjh,
Ctsktm1(cre)Ska,
Dlx5tm1(cre/ERT2)Zjh,
En1tm2(cre)Wrst,
Gad2tm2(cre)Zjh,
Gt(ROSA)26Sortm1.1(cre)Jphe,
Gt(ROSA)26Sortm1(cre/ERT2)Tyj,
Gt(ROSA)26Sortm1(FLP1)Dym,
Gt(ROSA)26Sortm2(icre/ERT2)Jphe,
Hnf4atm1(cre)Sdv,
Hprttm1(cre)Mnn,
Hsd11b2tm1(cre)Anft,
Krt19tm1(cre)Mmt,
Lyz2tm1(cre)Ifo,
Mapttm1(cre)Nagy,
Mnx1tm4(cre)Tmj,
Myf5tm3(cre)Sor,
Omptm4(cre)Mom,
Osr1tm1(EGFP/cre/ERT2)Amc,
Pax3tm1(cre)Joe,
Plekha5Tg(AMH-cre)1Flor,
Pvalbtm1(cre)Arbr,
Runx1tm1(cre/Esr1*)Ims,
Runx1tm2.1(cre/Esr1*)Ims,
Shhtm1(EGFP/cre)Cjt,
Six1tm1(cre,ALPP)Xli,
Sox17tm1(icre)Heli,
Sox17tm2.1(icre)Heli,
Ssttm2.1(cre)Zjh,
Tg(Abpa-cre)1Cmal,
Tg(Acta2-cre/ERT2)12Pcn,
Tg(Acta2-cre/ERT2)51Pcn,
Tg(ACTB-cre)1Tes,
Tg(ACTFLPe)9205Dym,
Tg(Adipoq-cre)1Evdr,
Tg(Alb1-cre)1Dlr,
Tg(Amh-cre)8815Reb,
Tg(Aqp2-cre)1Dek,
Tg(ATP6V1B1-cre)45Rnel,
Tg(CAG-cre/Esr1*)1Lbe,
Tg(Camk2a-cre)T29-1Stl,
Tg(CD2-cre)4Kio,
Tg(Cdh16-cre)91Igr,
Tg(Cdh5-cre)7Mlia,
Tg(Cdh5-cre/ERT2)CIVE23Mlia,
Tg(Cga-cre)3Sac,
Tg(Chst4-cre)1Hkwa,
Tg(Cyp11a1-cre)16Mchu,
Tg(Cyp17a1-cre)ACmk,
Tg(CYP19A1-cre)1Jri,
Tg(Cyp19a1-cre)5909Gle,
Tg(Cyp19a1-cre)5912Gle,
Tg(Ddx4-cre)1Dcas,
Tg(Ddx4-cre/ERT2)1Dcas,
Tg(Dhh-cre)1Mejr,
Tg(dlx6a-cre)1Mekk,
Tg(DMRT1-cre)1Svs,
Tg(EIIa-cre)C5379Lmgd,
Tg(Eno2-cre)2Lfp,
Tg(Fabp4-cre)1Rev,
Tg(FOXJ1-cre)F26Htzm,
Tg(Fshr-cre)1Ldu,
Tg(Gata1-cre)1Sho,
Tg(Gcm1-cre)1Chrn,
Tg(Gdf9-cre)5092Coo,
Tg(GFAP-cre)25Mes,
Tg(GFAP-cre/Esr1*,-lacZ)ASbk,
Tg(GFAP-cre/Esr1*,-lacZ)BSbk,
Tg(Gh1-cre)1Sac,
Tg(Gh1-cre)bKnmn,
Tg(Grik4-cre)G32-4Stl,
Tg(Hoxb7-cre)13Amc,
Tg(Hspa2-cre)1Eddy,
Tg(Inha-cre)1Zuk,
Tg(Inha-cre)2Zuk,
Tg(Inha-cre)3Zuk,
Tg(Ins2-cre)25Mgn,
Tg(Itgax-cre)1-1Reiz,
Tg(Kap-cre)29066/2Sig,
Tg(Kera-cre)KC4.3Wwk,
Tg(Kit-cre)143Hmb,
Tg(KLK3-cre)13Saa,
Tg(KRT14-cre)1Amc,
Tg(KRT14-cre)1Cgn,
Tg(KRT14-cre/ERT)20Efu,
Tg(KRT1-5-cre)5132Jlj,
Tg(KRT18-cre/ERT2)1Rgo,
Tg(KRT5-cre/ERT)ICmch,
Tg(KRT5-cre/ERT)SCmch,
Tg(Lck-cre)548Jxm,
Tg(Lhb-cre)1Sac,
Tg(Mbp-cre)6Gvn,
Tg(Mbp-cre)9Gvn,
Tg(MMTV-cre)1Mam,
Tg(MMTV-cre)4Mam,
Tg(MMTV-cre)FMam,
Tg(Msx2-cre)5Rem,
Tg(Mx1-cre)29-4Her,
Tg(Myh11-cre,-EGFP)2Mik,
Tg(Nes-cre)1Kln,
Tg(Neurog3-cre)24Syos,
Tg(Neurog3-cre)C1Able,
Tg(Nr5a1-cre)1Kmor,
Tg(Nr5a1-cre)2Klp,
Tg(Nr5a1-cre)2Lowl,
Tg(Nr5a1-cre)7Lowl,
Tg(Osr1-cre)4Mrt,
Tg(Pax2-cre)10Shwl,
Tg(Pbsn-cre)20Fwan,
Tg(Pbsn-cre)4Prb,
Tg(Pcp2-cre)1Amc,
Tg(Pcp2-cre)2Mpin,
Tg(Pf4-cre)Q3Rsko,
Tg(Pgk2-cre)1Yna,
Tg(Plp1-cre/ERT)3Pop,
Tg(Pomc1-cre)16Lowl,
Tg(Pres-cre)1Jnz,
Tg(Prm1-cre)1Osb,
Tg(Prnp-cre/ERT)28.8Ics,
Tg(Rarb-cre)1Bhr,
Tg(REN-cre)1Haca,
Tg(Rxfp2-cre)1Aia,
Tg(Rxfp2-cre)5Aia,
Tg(S100a4-cre)1Egn,
Tg(Slco1c1-icre/ERT2)1Mrks,
Tg(Sprr2f-cre)1Dcas,
Tg(Stra8-cre)1Reb,
Tg(Sycp1-cre)4Min,
Tg(Tagln-cre)1Her,
Tg(Tbx18-icre)1Fech,
Tg(Tek-cre)5326Sato,
Tg(Tek-cre/ERT2)1Soff,
Tg(Tex101-icre)2Lzj,
Tg(Thy1-cre)1Vln,
Tg(Tie1-cre)9Ref,
Tg(Tmem100-EGFP/cre/ERT2)30Amc,
Tg(TSPY-cre)33aYfcl,
Tg(Vav1-cre)1Awr,
Tg(Vav1-cre)8Cgp,
Tg(Vav1-cre)A2Kio,
Tg(Vil-cre)997Gum,
Tg(Wfs1-cre/ERT2)3Aibs,
Tg(Wnt1-cre)11Rth,
Tg(Zp3-cre)93Knw,
Thtm1(cre)Te,
Twist2tm1.1(cre)Dor,
Viptm1(cre)Zjh
(less)
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Images
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J:184578
Fig. Sim1 Ovary Uterus Adult
J:184578
Fig. Sim1 Testis Epididymis Adult
J:184578
Fig. Sim1 Testis Epididymis P7
J:184578
Fig. Sim1 Uterus P7
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Recombinase Activity
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Click heading to resort table.
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References
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Analysis Tools