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Allele Information
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Allele:
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Tg(Mef2c-cre)1Blk
transgene insertion 1, Brian L Black
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Driver: Mef2c
Type: Transgenic (Cre/Flp)
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Synonym:
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line 441G, mef2c-73k-Cre
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Molecular description:
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Cre recombinase is under the control of a 954-bp highly conserved promoter active in all skeletal muscles. Five of eight founder lines induced recombination when crossed to R26R reporter mice. 3 lines (44K, 441G and 453G) showed robust cre activity at E11.5 in skeletal muscle exclusively. The line created here represents line 441G.
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Find mice (IMSR):
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Mouse Strains:
1 lines available
Cell Lines:
0 lines available
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Additional Tissues:
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Tg(Mef2c-cre)1Blk activity also observed in:
embryo-other,
limbs,
mesenchyme,
muscle,
tail
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Tissue Information
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Postnatal-other
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Other recombinase alleles with activity in Postnatal-other tissues:
Acantm1(cre/ERT2)Crm,
Corttm1(cre)Zjh,
Ctsktm1(cre)Ska,
Dlx5tm1(cre/ERT2)Zjh,
En1tm2(cre)Wrst,
Gad2tm2(cre)Zjh,
Gt(ROSA)26Sortm1.1(rtTA,tetO-cre)Bkmn,
HhatTg(TFAP2A-cre)1Will,
Hprttm1(cre)Mnn,
Hsd11b2tm1(cre)Anft,
Myf5tm1.1(cre)Mrc,
Myf5tm3(cre)Sor,
Omptm4(cre)Mom,
Pax3tm1(cre)Joe,
Shhtm1(EGFP/cre)Cjt,
Slc6a3tm1.1(cre)Bkmn,
Ssttm2.1(cre)Zjh,
Tg(Acp5-cre)3Rda,
Tg(Acp5-cre)4Rda,
Tg(Acvrl1-cre)B1Spo,
Tg(Acvrl1-cre)L1Spo,
Tg(Bglap2-cre)2Kry,
Tg(CAG-cre)2Osb,
Tg(CD2-cre)4Kio,
Tg(Cdh5-cre)7Mlia,
Tg(Cdh5-cre/ERT2)CIVE23Mlia,
Tg(Col10a1-cre)1427Vdm,
Tg(Col10a1-cre)1Xya,
Tg(Col11a2-cre)4Nhzi,
Tg(Col1a1-cre)1Bek,
Tg(Col1a1-cre)1Kry,
Tg(Col1a1-cre)2Bek,
Tg(Col1a1-cre/ERT2)1Crm,
Tg(Col1a2-cre/ERT)7Cpd,
Tg(Col2a1-cre)1Bhr,
Tg(Col2a1-cre)1Star,
Tg(Col2a1-cre)1Xya,
Tg(Col2a1-cre/ERT)1Flng,
Tg(Col2a1-cre/ERT2)1Dic,
Tg(Col2a1-cre/ERT)KA3Smac,
Tg(Col2a1-rtTA,tetO-cre)22Pjro,
Tg(Col6a1-cre)1Gkl,
Tg(Csrp1-cre)1Sjc,
Tg(Ctsk-cre)1Rda,
Tg(Ctsk-cre)8Rda,
Tg(Ddx4-cre)1Dcas,
Tg(Dmp1-cre)1Jqfe,
Tg(EIIa-cre)C5379Lmgd,
Tg(Fabp4-cre)1Rev,
Tg(GFAP-cre)25Mes,
Tg(Grik4-cre)G32-4Stl,
Tg(Ins2-cre)25Mgn,
Tg(Itgam-cre)AJva,
Tg(Itgax-cre)1-1Reiz,
Tg(KRT14-cre)1Efu,
Tg(Mitf-cre)710-59Gsb,
Tg(Mitf-cre)7114Gsb,
Tg(Pax3-cre)2Joe,
Tg(Pcp2-cre)1Amc,
Tg(Pf4-cre)Q3Rsko,
Tg(Postn-cre)1Sjc,
Tg(Pres-cre)1Jnz,
Tg(rtetR-TetO-cre)40Mhz,
Tg(Runx2-icre)1Jtuc,
Tg(Sp7-tTA,tetO-EGFP/cre)1Amc,
Tg(Tagln-cre)1Her,
Tg(Thy1-cre)1Vln,
Tg(TSPY-cre)33aYfcl,
Twist2tm1.1(cre)Dor,
Twist2tm1(cre)Dor
(less)
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Images
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J:99340
Fig. 3
J:99340
Fig. 4
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Recombinase Activity
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Click heading to resort table.
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References
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Analysis Tools