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Tg(Mef2c-cre)1Blk - Limbs
Recombinase Activity Detail
Allele Information
Allele:
Tg(Mef2c-cre)1Blk
transgene insertion 1, Brian L Black
Driver: Mef2c
Type: Transgenic (Recombinase)
Synonym: line 441G, mef2c-73k-Cre
Molecular description: Cre recombinase is under the control of a 954-bp highly conserved promoter active in all skeletal muscles. Five of eight founder lines induced recombination when crossed to R26R reporter mice. 3 lines (44K, 441G and 453G) showed robust cre activity at E11.5 in skeletal muscle exclusively. The line created here represents line 441G.
Find mice (IMSR): Mouse Strains: 1 strain available       Cell Lines: 0 lines available
Additional Tissues: Tg(Mef2c-cre)1Blk activity also observed in:
embryo-other, mesenchyme, muscle, tail
Tissue Information
Limbs Other recombinase alleles with activity in Limbs tissues:
Images
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J:99340 Fig. 3 J:99340 Fig. 4 J:99340 Fig. 5
Recombinase Activity
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Assays Genotypic Background Result Notes  
References
All for this allele: 5 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
09/09/2014
MGI 5.19
The Jackson Laboratory