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Tg(Neurog3-cre)C1Able - Nervous System
Recombinase Activity Detail
Allele Information
Allele:
Tg(Neurog3-cre)C1Able
transgene insertion C1, Andrew B Leiter
Driver: Neurog3
Type: Transgenic (Recombinase)
Synonym: Neurog3(cre), ngn3-Cre, Tg(Neurog3-cre)#Able
Molecular description: The Cre recombinase coding sequence, flanked by a nuclear localization signal and an SV40 polyadenylation site, was inserted just after the translation start site of the neurogenin 3 gene present in mouse BAC RP23-121F10, which also includes approximately 81 kb of 5' and 102 kb of 3' flanking DNA. Immunohistochemical analysis shows the same expression pattern for cre as for neurogenin 3 in adult and embryonic mice bearing this transgene. Cre recombinase activity is seen in cell types of pancreas, stomach, small intestine and colon that express or are descended from cells that express neurogenin 3 during development.
Find mice (IMSR): Mouse Strains: 2 strains available       Cell Lines: 0 lines available
Additional Tissues: Tg(Neurog3-cre)C1Able activity also observed in:
alimentary system, embryo-other, hemolymphoid system, renal and urinary system, reproductive system
Tissue Information
Nervous System Other recombinase alleles with activity in Nervous System tissues:
Images
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Fig. Neurog3 Brain P56
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Fig. Neurog3 Brain P7
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Fig. Neurog3 Embryo 1b E10.5
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Fig. Neurog3 Embryo 2b E10.5
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Fig. Neurog3 Hypothalamus E15.5
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Fig. Neurog3 Sp Cord 2 P56
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Fig. Neurog3 Sp Cord 2 P7
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Fig. Neurog3 Sp Cord 3 P56
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Fig. Neurog3 Sp Cord 3 P7
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Fig. Neurog3 Sp Cord P56
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Fig. Neurog3 Sp Cord P7
Recombinase Activity
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Assays Genotypic Background Result Notes  
References
All for this allele: 37 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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Funding Information
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last database update
12/09/2014
MGI 5.20
The Jackson Laboratory