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Allele Information
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Allele:
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Synonym:
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Neurog3(cre), Tg(Neurog3-cre)#Able, ngn3-Cre
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Molecular description:
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The Cre recombinase coding sequence, flanked by a nuclear localization signal and an SV40 polyadenylation site, was inserted just after the translation start site of the neurogenin 3 gene present in mouse BAC RP23-121F10, which also includes approximately 81 kb of 5' and 102 kb of 3' flanking DNA. Immunohistochemical analysis shows the same expression pattern for cre as for neurogenin 3 in adult and embryonic mice bearing this transgene. Cre recombinase activity is seen in cell types of pancreas, stomach, small intestine and colon that express or are descended from cells that express neurogenin 3 during development.
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Find mice (IMSR):
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Mouse Strains:
2 lines available
Cell Lines:
0 lines available
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Additional Tissues:
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Tg(Neurog3-cre)C1Able activity also observed in:
embryo-other,
endocrine system,
hemolymphoid system,
nervous system,
renal and urinary system,
reproductive system
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Tissue Information
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Alimentary System
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Other recombinase alleles with activity in Alimentary System tissues:
1700009P17Riktm1.1(icre)Heli,
Airetm3(cre)Mmat,
Ascl3tm1(EGFP/cre)Ovi,
Atoh1tm1(cre)Gan,
Calb2tm1(cre)Zjh,
Ccktm1.1(cre)Zjh,
Chattm1(cre)Lowl,
Cldn6tm1(cre/ERT2)Dam,
Cpa1tm1(cre/ERT2)Dam,
Crhtm1(cre)Zjh,
Emx1tm1(cre)Krj,
En1tm2(cre)Wrst,
Fgf16tm1.1(cre)Sms,
Foxa2tm2.1(cre/Esr1*)Moon,
Foxg1tm1(cre)Skm,
Foxn1tm3(cre)Nrm,
Gad2tm2(cre)Zjh,
Grhl3tm1(cre)Cgh,
Gt(ROSA)26Sortm1(cre/ERT2)Tyj,
Gt(ROSA)26Sortm1(cre/ERT)Brn,
Gt(ROSA)26Sortm2(cre/ERT2)Brn,
HhatTg(TFAP2A-cre)1Will,
Hnf4atm1(cre)Sdv,
Hprttm1(cre)Mnn,
Hsd11b2tm1(cre)Anft,
Krt19tm1(cre/ERT)Ggu,
Krt19tm1(cre)Mmt,
Lgr5tm1(cre/ERT2)Cle,
Lyz2tm1(cre)Ifo,
Mcm2tm1(cre/ERT2)Scpr,
Mnx1tm4(cre)Tmj,
Myf5tm3(cre)Sor,
Ncr1tm1.1(icre)Viv,
Nkx2-5tm1(cre)Rjs,
Nkx2-5tm2(cre)Rph,
Nkx3-2tm3.1(cre)Tlu,
Nkx3-2tm4.1(cre)Tlu,
Notch1tm3(cre)Rko,
Omptm4(cre)Mom,
Osr2tm2(cre)Jian,
Pax3tm1(cre)Joe,
Plekha5Tg(AMH-cre)1Flor,
Ptf1atm1.1(cre)Cvw,
Runx1tm1(cre/Esr1*)Ims,
Shhtm1(EGFP/cre)Cjt,
Six1tm1(cre,ALPP)Xli,
Sox17tm1(icre)Heli,
Sox17tm2.1(icre)Heli,
Ssttm2.1(cre)Zjh,
Taglntm1(cre/ERT2)Feil,
Taglntm2(cre)Yec,
Tg(Acp5-cre)3Rda,
Tg(Acp5-cre)4Rda,
Tg(Acta2-cre/ERT2)12Pcn,
Tg(Acta2-cre/ERT2)51Pcn,
Tg(ACTC1-cre)1Miwa,
Tg(Acvrl1-cre)L1Spo,
Tg(Adipoq-cre)1Evdr,
Tg(Aire-cre)410-5Mmat,
Tg(Alb1-cre)1Dlr,
Tg(Amy2-cre)1Herr,
Tg(Atp4b-cre)1Jig,
Tg(Atp4b-cre)3Xya,
Tg(ATP6V1B1-cre)45Rnel,
Tg(Avil-cre)1Phep,
Tg(CA2-cre)1Subw,
Tg(CAG-cre/Esr1*)1Lbe,
Tg(CAG-cre/Esr1*)5Amc,
Tg(CAG-cre/Esr1*)86Lbgn,
Tg(Capn8-cre)1Xya,
Tg(Car1-cre)5Flt,
Tg(CD2-cre)4Kio,
Tg(Cdh5-cre)7Mlia,
Tg(Cdh5-cre/ERT2)CIVE23Mlia,
Tg(CDX2-cre)101Erf,
Tg(CDX2-cre*)189Erf,
Tg(Chst4-cre)1Hkwa,
Tg(Cma1-cre)6Thhe,
Tg(CMV-cre)1Cgn,
Tg(Col1a1-cre/ERT2)1Crm,
Tg(Col1a2-cre)23Angl,
Tg(Col1a2-cre/ERT)7Cpd,
Tg(Col2a1-cre)1Asz,
Tg(Col2a1-cre)1Bhr,
Tg(Col6a1-cre)1Gkl,
Tg(Csf1r-icre)1Jwp,
Tg(Ctsk-cre)1Rda,
Tg(Ctsk-cre)8Rda,
Tg(Cyp1a1-cre)1Dwi,
Tg(Cyp1a1-cre/ERT)1Dwi,
Tg(DBH-cre)6-8Koba,
Tg(DBH-cre)9-9Koba,
Tg(Dbh-icre)1Gsc,
Tg(Dll1-cre)33Dchp,
Tg(dlx6a-cre)1Mekk,
Tg(Dmp1-cre)1Jqfe,
Tg(Dspp-cre)1Kul,
Tg(ED-L2-cre)267Jkat,
Tg(EIIa-cre)C5379Lmgd,
Tg(Eno2-cre)2Lfp,
Tg(Fabp1-cre)1Jig,
Tg(Fabp1-cre-GH1)1Jig,
Tg(Fabp4-cre)1Rev,
Tgfb3tm1(cre)Vk,
Tg(Foxa2*-cre)#Mku,
Tg(Foxa3-cre)1Khk,
Tg(Foxl1-cre)1Khk,
Tg(Gcg-cre)1Herr,
Tg(GFAP-cre)25Mes,
Tg(GFAP-cre/Esr1*,-lacZ)ASbk,
Tg(GFAP-cre/Esr1*,-lacZ)BSbk,
Tg(Grik4-cre)G32-4Stl,
Tg(GZMB-cre)1Jcb,
Tg(Hand2-cre)7-1Clou,
Tg(Hhex-cre,-GFP)1Ksz,
Tg(Hoxa1-cre)1Tlu,
Tg(Hoxb3-cre)1Pkht,
Tg(Hoxb6-cre)C33Mku,
Tg(Hoxb7-cre)13Amc,
Tg(Hspa2-cre)1Eddy,
Tg(Il7-cre)CRche,
Tg(Ins2-cre)23Herr,
Tg(Ins2-cre)25Mgn,
Tg(INS-icre)18Msdr,
Tg(Itgax-cre)1-1Reiz,
Tg(Kdr-cre)15962Brei,
Tg(KRT14-cre)1Amc,
Tg(KRT14-cre)1Cgn,
Tg(KRT14-cre)1Efu,
Tg(KRT14-cre)1Ipc,
Tg(KRT14-cre)43Smr,
Tg(KRT14-cre)8Brn,
Tg(KRT1-5-cre)5132Jlj,
Tg(Krt2-6a-cre)1Ism,
Tg(KRT5-cre/ERT)ICmch,
Tg(KRT5-cre/ERT)SCmch,
Tg(mI56i-cre)6-2Clou,
Tg(MMTV-cre)1Mam,
Tg(MMTV-cre)4Mam,
Tg(Mpz-cre)94Imeg,
Tg(Mx1-cre)1Cgn,
Tg(Mx1-cre)29-4Her,
Tg(Myh11-cre)5013Gko,
Tg(Myh11-cre,-EGFP)2Mik,
Tg(Myh11-cre/ERT2)1Soff,
Tg(MYOD1-cre)M23Glh,
Tg(Nes-cre)1Atp,
Tg(Nes-cre)1Kln,
Tg(Nes-cre/ERT2)73Lfp,
Tg(Neurog3-cre)1Dam,
Tg(NEUROG3-cre)1Herr,
Tg(Neurog3-cre/Esr1*)1Dam,
Tg(Nkx2-1-cre)2Sand,
Tg(Nkx2-5-cre)9Eno,
Tg(Osr1-cre)4Mrt,
Tg(Pax6-cre)1Rilm,
Tg(Pax6-cre,GFP)1Pgr,
Tg(Pdgfb-icre/ERT2)1Frut,
Tg(Pdx1-cre)1Herr,
Tg(Pdx1-cre)6Cvw,
Tg(Pf4-cre)Q3Rsko,
Tg(Pitx3-cre/ERT2)1Ydq,
Tg(Plp1-cre/ERT)3Pop,
Tg(rtetR-TetO-cre)40Mhz,
Tg(S100a4-cre)1Egn,
Tg(Sftpa1-cre)1Xya,
Tg(Sim1-cre)1Lowl,
Tg(Smad7-cre)1Sjc,
Tg(Tagln-cre)1Her,
Tg(Tagln-cre)1Jjl,
Tg(Tal1-cre/ERT)1Jrg,
Tg(Tal1-cre/ERT)42-056Jrg,
Tg(T-cre)1Lwd,
Tg(Tek-cre)12Flv,
Tg(Tek-cre)1Arnd,
Tg(Tek-cre/ERT2)1Arnd,
Tg(tetO-cre)1Jaw,
Tg(tetO-cre)3Jig,
Tg(Thy1-cre)1Vln,
Tg(Thy1-cre)703Vaw,
Tg(Tlx2-cre)#Mori,
Tg(Tnni3-cre/GFP)1Mknn,
Tg(TPO-cre)1Shk,
Tg(Tyr-cre)1Gfk,
Tg(Tyrp1-cre)1Ipc,
Tg(Ure2-cre)1Jlr,
Tg(Vav1-cre)8Cgp,
Tg(Vav1-cre)A2Kio,
Tg(Vil-cre)1Mka,
Tg(Vil-cre)20Syr,
Tg(Vil-cre)997Gum,
Tg(Vil-cre/ERT2)23Syr,
Tg(Wap-cre)11738Mam,
Tg(Wfs1-cre/ERT2)3Aibs,
Tg(Wnt1-cre)11Rth,
Tg(WT1-cre)AG11Dbdr,
Thtm1(cre)Te,
Twist2tm1.1(cre)Dor,
Viptm1(cre)Zjh
(less)
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Images
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J:184579
Fig. Neurog3 Gut E15.5
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Fig. Neurog3 Intest P7
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Fig. Neurog3 Pancreas E15.5
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Fig. Neurog3 Stomach Adult
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Fig. 1
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Fig. 2
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Fig. 3
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Fig. 4
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Recombinase Activity
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Click heading to resort table.
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References
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Analysis Tools