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Tg(Myh6-cre/Esr1*)1Jmk - Cardiovascular System
Recombinase Activity Detail
Allele Information
Allele:
Tg(Myh6-cre/Esr1*)1Jmk
transgene insertion 1, Jeffery D Molkentin
Driver: Myh6
Type: Transgenic (Inducible, Recombinase)
Inducer: induced by tamoxifen
Synonym: alphaMHC-Cre-Mer-Cre, alpha-MHC-MerCreMer, MCM, mer, mER-CRE-mER, MerCreMer, Tg(Myh6-cre/Esr1)1Jmk
Molecular description: This transgene expresses a cre recombinase/ mutant estrogen receptor ligand binding domain fusion protein under the control of a mouse cardiac-specific alpha-myosin heavy chain promoter. Expression was detected in the juvenile and adult heart, but the protein is inactive until induced with tamoxifen.
Find mice (IMSR): Mouse Strains: 2 strains available       Cell Lines: 0 lines available
Tissue Information
Cardiovascular System Other recombinase alleles with activity in Cardiovascular System tissues:
Images
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J:206504 Full image
Fig. Myh6 Adult Heart
J:206504 Full image
Fig. Myh6 Adult Lung
Recombinase Activity
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Assays Genotypic Background Result Notes  
References
All for this allele: 142 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
12/09/2014
MGI 5.20
The Jackson Laboratory