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Twist2tm1(cre)Dor - Limbs
Recombinase Activity Detail
Allele Information
Allele:
Twist2tm1(cre)Dor
twist basic helix-loop-helix transcription factor 2; targeted mutation 1, David M Ornitz
Driver: Twist2
Type: Targeted (Recombinase)
Synonym: Dermo1cre, Dermo-1Cre, Dermo1-Cre, Dermocre, DM1-Cre, twist-2-, Twist2tm1(cre)Eno
Molecular description: Exon 1 was replaced with a cre recombinase gene and an FRT-flanked neo cassette. Southern blot analysis confirmed recombination. Cre was expressed in the developing skeleton, specifically in mesenchymal condensations giving rise to both osteoblast and chondrocyte lineages.
Find mice (IMSR): Mouse Strains: 0 strains available       Cell Lines: 0 lines available
Additional Tissues: Twist2tm1(cre)Dor activity also observed in:
branchial arches, embryo-other, integumental system, mesenchyme, postnatal-other, skeletal system
Tissue Information
Limbs Other recombinase alleles with activity in Limbs tissues:
Images
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J:90391 Fig. 1
Recombinase Activity
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Assays Genotypic Background Result Notes  
References
All for this allele: 45 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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Funding Information
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last database update
12/09/2014
MGI 5.20
The Jackson Laboratory