About   Help   FAQ
HhatTg(TFAP2A-cre)1Will - Muscle
Recombinase Activity Detail
Allele Information
Allele:
HhatTg(TFAP2A-cre)1Will
hedgehog acyltransferase; transgene insertion 1, Trevor Williams
Driver: TFAP2A
Type: Transgenic (Null/knockout, Recombinase)
Synonym: Ap2-Cre, AP-2CRE, CrefaceT
Molecular description: This transgenic construct consisted of 200 bp of human TFAP2A (TCFAP2A) promoter sequence (encoding a specific enhancer element) followed by NLS-cre, an SV40 polyA signal, and a 1.8 kb TFAP2A genomic fragment extending from within exon 5 through a portion of exon 6. The human intron 5 sequence includes the frontonasal prominence- and limb-specific enhancer. Expression of cre recombinase was detected in the embryonic face and limb mesenchyme. New research has determined that the transgene inserted into intron 9 of the Hhat locus. This insertion creates a non-functional allele.
Find mice (IMSR): Mouse Strains: 0 strains available       Cell Lines: 0 lines available
Additional Tissues: HhatTg(TFAP2A-cre)1Will activity also observed in:
Tissue Information
Muscle Other recombinase alleles with activity in Muscle tissues:
Images
Drag images to compare to others or to data in the table below. Drag corners to resize images for more detail. Reset Images
J:88829 Fig. 3
Recombinase Activity
Click heading to re-sort table.
Assays Genotypic Background Result Notes  
References
All for this allele: 7 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
12/23/2014
MGI 5.20
The Jackson Laboratory