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Allele Information
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Allele:
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Tg(Pdx1-cre)89.1Dam
transgene insertion 89.1, Douglas A Melton
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Driver: Pdx1
Type: Transgenic (Cre/Flp)
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Synonym:
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Pdx1-Creearly, Tg(Ipf1-cre)89.1Dam, Pdx1-Cretg, pPdx1-Cre, Pdx1Cre, Pdx1-Cre, PDX-cre
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Molecular description:
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Sequence encoding cre recombinase was adjoined to a mouse 5.5 kb region containing Pdx1 regulatory sequences. This promoter drives expression of cre recombinase in the pancreas. Expression was observed in the acini, islets, and ducts but not in mesenchymal cells (endothelial and mesenchyme-derived smooth muscle cells). Robust cre expression can be detected by E10.5 in pancreatic epithelium.
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Find mice (IMSR):
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Mouse Strains:
2 lines available
Cell Lines:
0 lines available
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Tissue Information
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Endocrine System
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Other recombinase alleles with activity in Endocrine System tissues:
1700009P17Riktm1.1(icre)Heli,
Ccktm1.1(cre)Zjh,
Cpa1tm1(cre/ERT2)Dam,
Fgf16tm1.1(cre)Sms,
Gt(ROSA)26Sortm1.1(cre)Jphe,
Gt(ROSA)26Sortm1(cre/ERT2)Tyj,
Gt(ROSA)26Sortm1(cre/ERT)Brn,
Gt(ROSA)26Sortm2(icre/ERT2)Jphe,
Hnf4atm1(cre)Sdv,
Hprttm1(cre)Mnn,
Krt19tm1(cre/ERT)Ggu,
Mnx1tm4(cre)Tmj,
Myf5tm3(cre)Sor,
Notch1tm3(cre)Rko,
Omptm4(cre)Mom,
Pax3tm1(cre)Joe,
Ptf1atm1.1(cre)Cvw,
Shhtm1(EGFP/cre)Cjt,
Ssttm2.1(cre)Zjh,
Tg(ACTB-cre)1Tes,
Tg(ACTFLPe)9205Dym,
Tg(Adipoq-cre)1Evdr,
Tg(Akr1b7-cre)1Anm,
Tg(Amy2-cre)1Herr,
Tg(CA2-cre)1Subw,
Tg(CA2-cre/Esr1*)1Subw,
Tg(CAG-cre/Esr1*)1Lbe,
Tg(CAG-cre/Esr1*)5Amc,
Tg(CAG-cre/Esr1*)86Lbgn,
Tg(Camk2a-cre)1Nobs,
Tg(Cdh5-cre)7Mlia,
Tg(Cdh5-cre/ERT2)CIVE23Mlia,
Tg(Cga-cre)3Sac,
Tg(CMV-cre)1Cgn,
Tg(Crx-cre)1Tfur,
Tg(Cyp11a1-cre)16Mchu,
Tg(Cyp17a1-cre)ACmk,
Tg(Cyp1a1-cre)1Dwi,
Tg(Cyp1a1-cre/ERT)1Dwi,
Tg(DBH-cre)6-8Koba,
Tg(DBH-cre)9-9Koba,
Tg(Dbh-cre/ERT2)198.1Hroh,
Tg(Dll1-cre)33Dchp,
Tg(EIIa-cre)C5379Lmgd,
Tg(Ela1-cre)16Eps,
Tg(Ela1-cre/ERT2)1Stof,
Tg(Fabp4-cre)1Rev,
Tg(Gcg-cre)1Herr,
Tg(Gcg-cre)1Slib,
Tg(GFAP-cre)25Mes,
Tg(Gh1-cre)1Sac,
Tg(Gh1-cre)bKnmn,
Tg(Ghrhr-cre)3242Lsk,
Tg(Grik4-cre)G32-4Stl,
Tg(Hoxb7-cre)13Amc,
Tg(Hspa2-cre)1Eddy,
Tg(Inha-cre)1Zuk,
Tg(Inha-cre)2Zuk,
Tg(Inha-cre)3Zuk,
Tg(Ins2-cre)23Herr,
Tg(Ins2-cre)25Mgn,
Tg(INS-icre)18Msdr,
Tg(Itgax-cre)1-1Reiz,
Tg(Kdr-cre)15962Brei,
Tg(Lhb-cre)1Sac,
Tg(Mbp-cre)6Gvn,
Tg(Mbp-cre)9Gvn,
Tg(MMTV-cre)4Mam,
Tg(Mx1-cre)1Cgn,
Tg(Nes-cre)1Kln,
Tg(Neurog3-cre)1Dam,
Tg(NEUROG3-cre)1Herr,
Tg(Neurog3-cre)C1Able,
Tg(Neurog3-cre/Esr1*)1Dam,
Tg(Nr5a1-cre)1Kmor,
Tg(Nr5a1-cre)2Klp,
Tg(Nr5a1-cre)2Lowl,
Tg(Nr5a1-cre)7Lowl,
Tg(Nr5a1-cre/ERT2)4Kmor,
Tg(Pax4-cre)1Dam,
Tg(Pax6-cre)1Rilm,
Tg(Pax6-cre,GFP)1Pgr,
Tg(Pcp2-cre)2Mpin,
Tg(Pdx1-cre)1Herr,
Tg(Pdx1-cre)6Cvw,
Tg(Pdx1-cre/Esr1*)35.10Dam,
Tg(Pdx1-cre/Esr1*)35.6Dam,
Tg(Pf4-cre)Q3Rsko,
Tg(Pgk1-cre)1Lni,
Tg(Pitx1-cre)1Rsd,
Tg(Pomc-cre)5Brn,
Tg(Prm-cre)58Og,
Tg(PTH-cre)4167Slib,
Tg(Rarb-cre)1Bhr,
Tg(REN-cre)1Haca,
Tg(Sim1-cre)1Lowl,
Tg(Sycp1-cre)4Min,
Tg(Tagln-cre)1Her,
Tg(Tek-cre)1Arnd,
Tg(Tek-cre)5326Sato,
Tg(Tek-cre/ERT2)1Arnd,
Tg(tetO-cre)1Jaw,
Tg(Tg-cre)1Soff,
Tg(Th-cre)12Mrub,
Tg(Th-cre)1Tmd,
Tg(Thy1-cre)1Vln,
Tg(TPO-cre)1Shk,
Tg(Tyr-cre)1Gfk,
Tg(Vav1-cre)8Cgp,
Tg(Vil-cre)997Gum,
Tg(Wfs1-cre/ERT2)3Aibs,
Tg(Wnt1-cre)11Rth,
Thtm1(cre)Te,
Twist2tm1.1(cre)Dor,
Viptm1(cre)Zjh
(less)
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Images
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J:136227
Fig. 5
J:136227
Fig. 5
J:76095
Fig. 2
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Recombinase Activity
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Click heading to resort table.
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References
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Analysis Tools