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Tg(Hoxb7-cre)13Amc - Nervous System
Recombinase Activity Detail
Allele Information
Allele:
Tg(Hoxb7-cre)13Amc
transgene insertion 13, Andrew P McMahon
Driver: Hoxb7
Type: Transgenic (Recombinase)
Synonym: Hoxb7-Cre, HoxB7Cre, HoxB7/Cre
Molecular description: A transgenic construct containing the 1.3Kb enhancer and promoter sequence upstream of the of mouse homeo box B7 gene, a human growth factor mini gene and the Cre coding sequence was injected into fertilized C57BL/6 mouse eggs. Cre recombinase expression is detected in the mesonephric duct as early as embryonic day 9.5, in the ureteric bud by embryonic day 10.25 and in all ureteric bud epithelial cells by embryonic day 12.5. Low levels of expression are detected in the dorsal root ganglia and the spinal cord.
Find mice (IMSR): Mouse Strains: 1 strain available       Cell Lines: 0 lines available
Additional Tissues: Tg(Hoxb7-cre)13Amc activity also observed in:
Tissue Information
Nervous System Other recombinase alleles with activity in Nervous System tissues:
Images
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J:137887 Fig. Hoxb7 a Body P0 J:137887 Fig. Hoxb7 Body P0 J:137887 Fig. Hoxb7 Brain 2 Adult J:137887 Fig. Hoxb7 Brain 3 Adult J:137887 Fig. Hoxb7 Brain Adult J:137887 Fig. Hoxb7 Brain b P7 J:137887 Fig. Hoxb7 Brain P7 J:137887 Fig. Hoxb7 Head b P0
J:137887 Fig. Hoxb7 Head P0 J:137887 Fig. Hoxb7 Lung Adult J:137887 Fig. Hoxb7 Muscle a P7 J:137887 Fig. Hoxb7 Muscle P7 J:137887 Fig. Hoxb7 Skel Muscle 2 Adult J:137887 Fig. Hoxb7 Skel Muscle Adult J:79481 Fig. 2 J:98831 Fig. 2
Recombinase Activity
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Assays Genotypic Background Result Notes  
References
All for this allele: 47 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
08/19/2014
MGI 5.19
The Jackson Laboratory