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Tg(Foxa3-cre)1Khk - Mesenchyme
Recombinase Activity Detail
Allele Information
Allele:
Tg(Foxa3-cre)1Khk
transgene insertion 1, Klaus H Kaestner
Driver: Foxa3
Type: Transgenic (Recombinase)
Synonym: Foxa3cre, Foxa3.cre, Foxa3Cre, Foxa3-Cre, Tg(Foxa3-cre)1Khk
Molecular description: The transgenic construct consists of a 170 kb fragment containing a modified Foxa3 locus in which exon 2 has been replaced with an IRES-cre cassette. Cre activity was first detected 8.5 dpc in the anterior intestinal portal, and later in the entire gut endoderm from stomach to colon. Efficient cre-mediated recombination was demonstrated in the stomach, liver, pancreas, and colon.
Find mice (IMSR): Mouse Strains: 1 strain available       Cell Lines: 0 lines available
Additional Tissues: Tg(Foxa3-cre)1Khk activity also observed in:
alimentary system, extraembryonic component, liver and biliary system, tail
Tissue Information
Mesenchyme Other recombinase alleles with activity in Mesenchyme tissues:
Recombinase Activity
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Assays Genotypic Background Result Notes  
References
All for this allele: 22 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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Funding Information
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last database update
12/09/2014
MGI 5.20
The Jackson Laboratory