About   Help   FAQ
Tg(Sox2-cre)1Amc - Embryo-other
Recombinase Activity Detail
Allele Information
Allele:
Tg(Sox2-cre)1Amc
transgene insertion 1, Andrew P McMahon 		Driver: Sox2
Type: Transgenic (Cre/Flp)
Synonym: Sox2::Cre, Sox2-cre, Sox2Cre
Molecular description: This transgene expresses Cre recombinase under the control of a mouse Sox2 promoter. Expression of this transgene is sex-dependent, with increased efficiency when passed through the female germline. When the transgene is passed through the male germline, cre activity is observed in epiblast cells as early as E6.5 of only those embryos that inherit the transgene and no expression is detected in extraembryonic tissue. When the transgene is passed through the female germline, cre activity is observed throughout the embryo (including the yolk sac) in all early embryos regardless of whether or not they inherit the transgene.
Find mice (IMSR): Mouse Strains: 4 lines available       Cell Lines: 0 lines available
Additional Tissues: Tg(Sox2-cre)1Amc activity also observed in:
early embryo, extraembryonic component
Tissue Information
Embryo-other Other recombinase alleles with activity in Embryo-other tissues:
Images
Drag images to compare to others or to data in the table below. Drag corners to resize images for more detail. Reset Images
J:83040
Fig. 1 J:83040
Fig. 2
Recombinase Activity
Click heading to resort table.
Assays Genotypic Background Result Notes  
References
All for this allele: 138 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support. 		last database update
05/08/2013
MGI 5.13 		The Jackson Laboratory