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Tg(Myh11-cre,-EGFP)2Mik - Reproductive System
Recombinase Activity Detail
Allele Information
Allele:
Tg(Myh11-cre,-EGFP)2Mik
transgene insertion 2, Michael I Kotlikoff 		Driver: Myh11
Type: Transgenic (Cre/Flp)
Synonym: smMHC/Cre/eGFP, MH, Tg(Myh11-cre/EGFP)1Mik, smMHC-Cre-IRES-eGFP, smMHCCre/eGFP, smMHC-Cre, smMHC-Cre-GFPtg
Molecular description: The transgene consists of a mouse Myh11 promoter, a cre recombinase gene, an internal ribosome entry site (IRES) and an enhanced GFP gene. 16 kb of mouse Myh11 promoter sequences was used to drive the bicistronic transgene expression in smooth muscle cells. The promoter has also been reported to be active in female germ cells. A low frequency of deletion events are also observed by inheritance from the male germline.
Find mice (IMSR): Mouse Strains: 1 lines available       Cell Lines: 0 lines available
Additional Tissues: Tg(Myh11-cre,-EGFP)2Mik activity also observed in:
alimentary system, cardiovascular system, nervous system, renal and urinary system, respiratory system, sensory organs
Tissue Information
Reproductive System Other recombinase alleles with activity in Reproductive System tissues:
Recombinase Activity
Click heading to resort table.
Assays Genotypic Background Result Notes  
References
All for this allele: 16 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
05/08/2013
MGI 5.13 		The Jackson Laboratory