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Tg(Tek-cre/ERT2)1Arnd - Liver And Biliary System
Recombinase Activity Detail
Allele Information
Allele:
Tg(Tek-cre/ERT2)1Arnd
transgene insertion 1, Bernd Arnold
Driver: Tek
Type: Transgenic (Cre/Flp)
Inducer: induced by tamoxifen
Synonym: L43Tie2CreT2, Tg(Tek-cre/ESR1)1Arnd, Tie2-CreERT2, Tie2ERT2Cre
Molecular description: The transgenic construct encodes a tamoxifen inducible fusion protein consisting of cre recombinase and a mutated human estrogen receptor ligand binding domain fused to the mouse Tek promoter and 10.5 kb of the first intron. Transgene expression in endothelial cells of the liver and kidney was confirmed by immunohistochemical analysis.
Find mice (IMSR): Mouse Strains: 2 lines available       Cell Lines: 0 lines available
Additional Tissues: Tg(Tek-cre/ERT2)1Arnd activity also observed in:
alimentary system, cardiovascular system, hemolymphoid system, nervous system, renal and urinary system, respiratory system
Tissue Information
Liver And Biliary System Other recombinase alleles with activity in Liver And Biliary System tissues:
Images
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J:81649 Fig. 3
Recombinase Activity
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Assays Genotypic Background Result Notes  
References
All for this allele: 15 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
04/08/2014
MGI 5.17
The Jackson Laboratory