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Nkx2-5tm2(cre)Rph - Mesenchyme
Recombinase Activity Detail
Allele Information
NK2 homeobox 5; targeted mutation 2, Richard P Harvey
Driver: Nkx2-5
Type: Targeted (No functional change, Recombinase)
Synonym: Nkx2.5-Cre, Nkx2-5IRESCre
Molecular description: Sequence encoding cre recombinase adjoined to an IRES was inserted into the 3' UTR of the endogenous locus via homologous recombination. A single frt site remained in the UTR after an frt-flanked hygromycin selection cassette was excised. A lack of observed allele complementation indicated that the inserted sequence did not significantly affect expression of the endogenous locus.
Find mice (IMSR): Mouse Strains: 1 strain available       Cell Lines: 0 lines available
Additional Tissues: Nkx2-5tm2(cre)Rph activity also observed in:
Tissue Information
Mesenchyme Other recombinase alleles with activity in Mesenchyme tissues:
Recombinase Activity
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Assays Genotypic Background Result Notes  
All for this allele: 22 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.03
The Jackson Laboratory