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Tg(Vil-cre)997Gum - Alimentary System
Recombinase Activity Detail
Allele Information
Allele:
Tg(Vil-cre)997Gum
transgene insertion 997, Deborah L Gumucio 		Driver: Vil1
Type: Transgenic (Cre/Flp)
Synonym: Vil-Cre, VillinCre, VilCre, Villin.cre, 12.4KbVilCre, Villin-cre, Tg(Vil-cre)997Gum
Molecular description: A 12.4-kb promoter fragment from the villin 1 gene drives the expression of cre recombinase. Recombination occurs in villi and crypt cells of the small and large intestines, closely patterning the endogenous gene expression. According to the corresponding author (J:78815), expression is generally continuous but a small amount of mosaicism is noted in the colon. Onset of transgene expression is at 12.5 dpc, which is delayed from the endogenous mouse Vil gene expression onset of 9.0 dpc.
Find mice (IMSR): Mouse Strains: 1 lines available       Cell Lines: 0 lines available
Additional Tissues: Tg(Vil-cre)997Gum activity also observed in:
cardiovascular system, endocrine system, nervous system, renal and urinary system, reproductive system, respiratory system
Tissue Information
Alimentary System Other recombinase alleles with activity in Alimentary System tissues:
Images
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J:184579
Fig. Vil Gut E15.5 J:184579
Fig. Vil Intestine Adult J:184579
Fig. Vil Intestine P7 J:78815
Fig. 8
Recombinase Activity
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Assays Genotypic Background Result Notes  
References
All for this allele: 132 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
05/22/2013
MGI 5.13 		The Jackson Laboratory