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Allele Information
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Allele:
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Tg(BGLAP-cre)1Clem
transgene insertion 1, Thomas L Clemens
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Driver: BGLAP
Type: Transgenic (Cre/Flp)
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Synonym:
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OCNCre, osteocalcin-Cre, HOC-cre, OC-cre line 6, OC-cre
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Molecular description:
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A human osteocalcin (BGLAP) promoter, driving expression in osteoblasts, fused to a cre recombinase gene was used for the transgene. The cre gene was modified to include a nuclear localization signal and human ACTB 3' untranslated region. Two lines were generated, 4 and 6. This allele represents line 6. Transgene expression was observed in the calvaria, femur, and vertebrae by Northern blot analysis.
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Find mice (IMSR):
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Mouse Strains:
1 lines available
Cell Lines:
0 lines available
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Tissue Information
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Skeletal System
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Other recombinase alleles with activity in Skeletal System tissues:
Calb2tm1(cre)Zjh,
Ccktm1.1(cre)Zjh,
Ctsktm1(cre)Ska,
En1tm2(cre)Wrst,
Myf5tm1.1(cre)Mrc,
Myf5tm3(cre)Sor,
Nkx3-2tm3.1(cre)Tlu,
Nkx3-2tm4.1(cre)Tlu,
Omptm4(cre)Mom,
Pax3tm1(cre)Joe,
Ssttm2.1(cre)Zjh,
Tg(CD2-cre)4Kio,
Tg(Cdh5-cre)7Mlia,
Tg(Cdh5-cre/ERT2)CIVE23Mlia,
Tg(Col1a1-cre)1Bek,
Tg(Col1a1-cre)1Kry,
Tg(Col1a1-cre)2Bek,
Tg(Col1a1-cre/ERT2)1Crm,
Tg(Col1a1-cre/Esr1*)1Mis,
Tg(Col1a1-cre)#Xya,
Tg(Col1a2-cre)23Angl,
Tg(Col1a2-cre/ERT)7Cpd,
Tg(Col2a1-cre)1Asz,
Tg(Col2a1-cre)1Bhr,
Tg(Col2a1-cre/ERT2)1Dic,
Tg(Col2a1-cre/ERT)KA3Smac,
Tg(dlx6a-cre)1Mekk,
Tg(EIIa-cre)C5379Lmgd,
Tg(Fabp4-cre)1Rev,
Tg(GFAP-cre)25Mes,
Tg(Hand2-cre)7-1Clou,
Tg(Hspa2-cre)1Eddy,
Tg(Ins2-cre)25Mgn,
Tg(Kdr-cre)15962Brei,
Tg(mI56i-cre)6-2Clou,
Tg(Nes-cre)1Atp,
Tg(Pcp2-cre)1Amc,
Tg(Pf4-cre)Q3Rsko,
Tg(S100b-EGFP/cre/ERT2)22Amc,
Tg(Sim1-cre)1Lowl,
Tg(Tagln-cre)1Her,
Tg(Thy1-cre)1Vln,
Twist2tm1.1(cre)Dor
(less)
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Images
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J:80190
Fig. 2
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Recombinase Activity
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Click heading to resort table.
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References
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Analysis Tools