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Pitx2tm4(cre)Jfm - Cardiovascular System
Recombinase Activity Detail
Allele Information
Allele:
Pitx2tm4(cre)Jfm
paired-like homeodomain transcription factor 2; targeted mutation 4, James F Martin 		Driver: Pitx2
Type: Targeted (knock-in)
Synonym: Pitx2 delta abccreneo, Pitx2creneo, Pitx2-Cre, delta abccreneo
Molecular description: Exon 5, which encodes a portion of the homeodomain, was disrupted by the insertion of a cassette containing IRES, cre recombinase, lacZ, and neo. In situ hybridization results showed that the expression pattern of cre was similar to that of the endogenous gene. The neo was removed by crossing to Flp-expressing mice.
Find mice (IMSR): Mouse Strains: 1 lines available       Cell Lines: 0 lines available
Tissue Information
Cardiovascular System Other recombinase alleles with activity in Cardiovascular System tissues:
Images
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J:79853
Fig. 5 J:79853
Fig. 6
Recombinase Activity
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Assays Genotypic Background Result Notes  
References
All for this allele: 11 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
05/08/2013
MGI 5.13 		The Jackson Laboratory