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Pitx2tm4(cre)Jfm - Cardiovascular System
Recombinase Activity Detail
Allele Information
paired-like homeodomain transcription factor 2; targeted mutation 4, James F Martin
Driver: Pitx2
Type: Targeted (Recombinase)
Synonym: delta abccreneo, Pitx2-Cre, Pitx2creneo, Pitx2 delta abccreneo
Molecular description: Exon 5, which encodes a portion of the homeodomain, was disrupted by the insertion of a cassette containing IRES, cre recombinase, lacZ, and neo. In situ hybridization results showed that the expression pattern of cre was similar to that of the endogenous gene. The neo was removed by crossing to Flp-expressing mice.
Find mice (IMSR): Mouse Strains: 1 strain available       Cell Lines: 0 lines available
Tissue Information
Cardiovascular System Other recombinase alleles with activity in Cardiovascular System tissues:
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J:79853 Fig. 5 J:79853 Fig. 6
Recombinase Activity
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Assays Genotypic Background Result Notes  
All for this allele: 16 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.03
The Jackson Laboratory