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Gt(ROSA)26Sortm1(cre/ERT)Brn - Liver And Biliary System
Recombinase Activity Detail
Allele Information
Allele:
Gt(ROSA)26Sortm1(cre/ERT)Brn
gene trap ROSA 26, Philippe Soriano; targeted mutation 1, Anton Berns
Driver: Gt(ROSA)26Sor
Type: Targeted (Inducible, Recombinase)
Inducer: induced by tamoxifen
Synonym: ACM-cre, Cre-ERTm, Gt(ROSA)26Sortm1(cre/Esr1)Brn, R26cre-ERT, R26-CreERT, R26Cre-ERT, Tx-Cre
Molecular description: A splice acceptor site followed by a cre gene and puromycin resistance cassette was inserted at the ROSA26 gene trap locus. Efficient Cre-mediated recombination in transgenic mice carrying floxed reporter genes was reported to reflect constitutive expression of the Gt(ROSA)26Sor from preimplantation stages onward.
Find mice (IMSR): Mouse Strains: 2 strains available       Cell Lines: 0 lines available
Additional Tissues: Gt(ROSA)26Sortm1(cre/ERT)Brn activity also observed in:
alimentary system, cavities and their linings, integumental system, renal and urinary system, respiratory system
Tissue Information
Liver And Biliary System Other recombinase alleles with activity in Liver And Biliary System tissues:
Recombinase Activity
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Assays Genotypic Background Result Notes  
References
All for this allele: 31 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
07/15/2014
MGI 5.18
The Jackson Laboratory