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Gt(ROSA)26Sortm1(cre/ERT)Brn - Integumental System
Recombinase Activity Detail
Allele Information
Allele:
Gt(ROSA)26Sortm1(cre/ERT)Brn
gene trap ROSA 26, Philippe Soriano; targeted mutation 1, Anton Berns
Driver: Gt(ROSA)26Sor
Type: Targeted (Inducible, Recombinase)
Inducer: induced by tamoxifen
Synonym: ACM-cre, Cre-ERTm, Gt(ROSA)26Sortm1(cre/Esr1)Brn, R26cre-ERT, R26-CreERT, R26Cre-ERT, Tx-Cre
Molecular description: A splice acceptor site followed by a cre gene and puromycin resistance cassette was inserted at the ROSA26 gene trap locus. Efficient Cre-mediated recombination in transgenic mice carrying floxed reporter genes was reported to reflect constitutive expression of the Gt(ROSA)26Sor from preimplantation stages onward.
Find mice (IMSR): Mouse Strains: 2 strains available       Cell Lines: 0 lines available
Additional Tissues: Gt(ROSA)26Sortm1(cre/ERT)Brn activity also observed in:
alimentary system, cavities and their linings, liver and biliary system, renal and urinary system, respiratory system
Tissue Information
Integumental System Other recombinase alleles with activity in Integumental System tissues:
Recombinase Activity
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Assays Genotypic Background Result Notes  
References
All for this allele: 31 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
08/12/2014
MGI 5.19
The Jackson Laboratory