About   Help   FAQ
Tg(CMV-cre/ERT)1Ipc - Integumental System
Recombinase Activity Detail
Allele Information
Allele:
Tg(CMV-cre/ERT)1Ipc
transgene insertion 1, I Pierre Chambon
Driver: CMV
Type: Transgenic (Inducible, Recombinase)
Inducer: induced by tamoxifen
Synonym: CMV-cre, CMV-Cre-ERT, CMV-CRE-ER-Tx, Cre-ERT, CRE-ER-Tx, Tg(CMV-cre/ESR1)1Ipc
Molecular description: The transgenic construct encodes a tamoxifen dependent cre recombinase. The cre recombinase coding region was joined to sequence encoding the ligand binding domain of the human estrogen receptor with a glycine to arginine missense mutation at position 521. This substitution enables the domain to bind to tamoxifen while ablating the estradiol binding ability. The transgene was driven by the CMV promoter.
Find mice (IMSR): Mouse Strains: 0 strains available       Cell Lines: 0 lines available
Tissue Information
Integumental System Other recombinase alleles with activity in Integumental System tissues:
Images
Drag images to compare to others or to data in the table below. Drag corners to resize images for more detail. Reset Images
J:79177 Fig. 2 J:79177 Fig. 3 J:79177 Fig. 4
Recombinase Activity
Click heading to re-sort table.
Assays Genotypic Background Result Notes  
References
All for this allele: 11 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
12/16/2014
MGI 5.20
The Jackson Laboratory