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Tg(CMV-cre/ERT)1Ipc - Integumental System
Recombinase Activity Detail
Allele Information
transgene insertion 1, I Pierre Chambon
Driver: CMV
Type: Transgenic (Inducible, Recombinase)
Inducer: tamoxifen
Synonym: CMV-cre, CMV-Cre-ERT, CMV-CRE-ER-Tx, Cre-ERT, CRE-ER-Tx, Tg(CMV-cre/ESR1)1Ipc
Molecular description: The transgenic construct encodes a tamoxifen dependent cre recombinase. The cre recombinase coding region was joined to sequence encoding the ligand binding domain of the human estrogen receptor with a glycine to arginine missense mutation at position 521. This substitution enables the domain to bind to tamoxifen while ablating the estradiol binding ability. The transgene was driven by the CMV promoter.
Find mice (IMSR): Mouse Strains: 0 strains available       Cell Lines: 0 lines available
Tissue Information
Integumental System Other recombinase alleles with activity in Integumental System tissues:
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J:79177 Fig. 2 J:79177 Fig. 3 J:79177 Fig. 4
Recombinase Activity
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Assays Genotypic Background Result Notes  
All for this allele: 13 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.03
The Jackson Laboratory