About   Help   FAQ
Tg(Nes-cre)1Wme - Nervous System
Recombinase Activity Detail
Allele Information
transgene insertion 1, Werner Muller
Driver: Nes
Type: Transgenic (Recombinase)
Synonym: bal1, Bal1 cre, balancer1, Nestin-Cre, SLNE4c, Tg(balancer1)2Cgn, TgN(balancer1)1Cgn, TgN(balancer1)2Cgn
Molecular description: The transgenic construct contained a nestin promoter followed by cre recombinase sequence adjoined to a nuclear localization signal. Intron 2 of the nestin gene was included upstream of a polyadenylation signal. While the endogenous nestin promoter is CNS-specific, Southern blot analysis showed the ubiquitous expression of cre in transgenic mice. Variable mosaicism/partial deletion of loxP-flanked alleles occurs before embryonic day 10.5, and it is detectable in all adult organs examined including germ line cells.
Find mice (IMSR): Mouse Strains: 1 strain available       Cell Lines: 0 lines available
Additional Tissues: Tg(Nes-cre)1Wme activity also observed in:
early embryo, embryo-other
Tissue Information
Nervous System Other recombinase alleles with activity in Nervous System tissues:
Drag images to compare to others or to data in the table below. Drag corners to resize images for more detail. Reset Images
J:75055 Fig. 1
Recombinase Activity
Click heading to re-sort table.
Assays Genotypic Background Result Notes  
All for this allele: 51 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
MGI 6.03
The Jackson Laboratory