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Myl2tm1(cre)Krc - Cardiovascular System
Recombinase Activity Detail
Allele Information
Allele:
Myl2tm1(cre)Krc
myosin, light polypeptide 2, regulatory, cardiac, slow; targeted mutation 1, Kenneth R Chien 		Driver: Myl2
Type: Targeted (knock-in)
Synonym: Mlc2v-cre, MLC-2v -, MLC2vcreKI, MLC2v-cre
Molecular description: Part of exon 1 and all of exon 2 were replaced with a cre gene and a floxed PGK-neo-tk cassette via homologous recombination. Western blot analysis showed that homozygous embryos did not express Myl2 protein product. The knocked in cre gene is expressed by the Myl2 promoter in ventricular tissue starting at day E7.5.
Find mice (IMSR): Mouse Strains: 1 lines available       Cell Lines: 0 lines available
Tissue Information
Cardiovascular System Other recombinase alleles with activity in Cardiovascular System tissues:
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J:163274
Fig. 2
Recombinase Activity
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Assays Genotypic Background Result Notes  
References
All for this allele: 76 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
05/08/2013
MGI 5.13 		The Jackson Laboratory