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Myl2tm1(cre)Krc - Cardiovascular System
Recombinase Activity Detail
Allele Information
myosin, light polypeptide 2, regulatory, cardiac, slow; targeted mutation 1, Kenneth R Chien
Driver: Myl2
Type: Targeted (Recombinase)
Synonym: MLC-2v -, Mlc2v-cre, MLC2v-cre, MLC2vcreKI
Molecular description: Part of exon 1 and all of exon 2 were replaced with a cre gene and a floxed PGK-neo-tk cassette via homologous recombination. Western blot analysis showed that homozygous embryos did not express Myl2 protein product. The knocked in cre gene is expressed by the Myl2 promoter in ventricular tissue starting at day E7.5.
Find mice (IMSR): Mouse Strains: 1 strain available       Cell Lines: 0 lines available
Tissue Information
Cardiovascular System Other recombinase alleles with activity in Cardiovascular System tissues:
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J:163274 Fig. 2
Recombinase Activity
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Assays Genotypic Background Result Notes  
All for this allele: 90 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.03
The Jackson Laboratory