Tg(Ckmm-cre)5Khn - Embryo-other Recombinase Activity Detail MGI Mouse

Tg(Ckmm-cre)5Khn - Embryo-other
Recombinase Activity Detail

Allele Information | Recombinase Activity | References

Allele Information

Allele:

Tg(Ckmm-cre)5Khn
transgene insertion 5, C Ronald Kahn

Driver: Ckm
Type: Transgenic (Recombinase)

Synonym:

Ckm-cre, Ckmm-cre, Ckmm-NLS-cre, Cre^Mck, mckCRE, MCK-cre, MCKCre⁺, MCK-cre5, Tg(Ckm-cre)5Khn, Tg(Ckmm-cre)1Khn

Molecular description:

A 6.5 kb genomic DNA fragment of the Ckmm gene containing the promoter and enhancer 1, untranslated exon 1, 3kb of intron 1 including the enhancer 2 region, and the first 16 bp of exon 2 drives expression of a modified cre with an SV40 large T antigen nuclear localization signal. Expression is directed to the heart and skeletal muscle.

Find mice (IMSR):

Mouse Strains: 4 strains available Cell Lines: 0 lines available

Additional Tissues:

Tg(Ckmm-cre)5Khn activity also observed in:

alimentary system, cardiovascular system, head, integumental system ...(more)

Recombinase Activity

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Assays Genotypic Background Result Notes

References

All for this allele:

382 reference(s)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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