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Hprttm1(cre)Mnn - Liver And Biliary System
Recombinase Activity Detail
Allele Information
Allele:
Hprttm1(cre)Mnn
hypoxanthine guanine phosphoribosyl transferase; targeted mutation 1, Jeffrey R Mann
Driver: CAG
Type: Targeted (Recombinase)
Synonym: Hprt1tm1(cre)Mnn, hprt-cre, Hprtcre, Hprttm1(CAG.cre)MdCoh
Molecular description: An expression cassette in which a CMV enhancer and chicken beta-globin promoter driving Cre recombinase expression was inserted in reverse transcriptional orientation into exon 3 of the gene. A PGK-neomycin selection cassette was also inserted following the cre gene. Expression of Cre recombinase occurred at high levels in the female germline and fertilized eggs, and all offspring of heterozyous females display excision of reporter sequences.
Find mice (IMSR): Mouse Strains: 1 strain available       Cell Lines: 0 lines available
Additional Tissues: Hprttm1(cre)Mnn activity also observed in:
Tissue Information
Liver And Biliary System Other recombinase alleles with activity in Liver And Biliary System tissues:
Images
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J:147304 Fig. 2
Recombinase Activity
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Assays Genotypic Background Result Notes  
References
All for this allele: 66 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
07/15/2014
MGI 5.18
The Jackson Laboratory