About   Help   FAQ
Tg(Col2a1-cre)10Amc - Limbs
Recombinase Activity Detail
Allele Information
Allele:
Tg(Col2a1-cre)10Amc
transgene insertion 10, Andrew P McMahon
Driver: Col2a1
Type: Transgenic (Cre/Flp)
Synonym: Col2-Cre, Col2-Cre10, CRE 10
Molecular description: This transgene expresses Cre recombinase under the control of the collagen II (Col2a1) promoter, which directs expression in all cartilagenous structures at E12.5, as well as the facial mesenchyme and the CNS. At E13.5, Cre-recombinase activity is detected in the skeletal structures of the developing appendicular, axial and cranial skeleton, such as long bones of limbs, ribs, vertebrae and skull base, as well as in the epithelial cells of kidney, pancreas, lungs, intestine and ovary.
Find mice (IMSR): Mouse Strains: 0 lines available       Cell Lines: 0 lines available
Additional Tissues: Tg(Col2a1-cre)10Amc activity also observed in:
embryo-other, mesenchyme, nervous system
Tissue Information
Limbs Other recombinase alleles with activity in Limbs tissues:
Recombinase Activity
Click heading to re-sort table.
Assays Genotypic Background Result Notes  
References
All for this allele: 8 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
04/15/2014
MGI 5.17
The Jackson Laboratory