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Speer6-ps1Tg(Alb-cre)21Mgn - Liver & Biliary System
Recombinase Activity Detail
Allele Information
Allele:
Speer6-ps1Tg(Alb-cre)21Mgn
spermatogenesis associated glutamate (E)-rich protein 6, pseudogene 1; transgene insertion 21, Mark A Magnuson
Driver: Alb
Type: Transgenic (Recombinase)
Synonym: Albcre, Alb-cre, AlbCre, Alb-Cre, Albcre2, albumin-cre, crAlb, CreALB, Tg(Alb-cre)21Mg
Molecular description: The transgene contains a 2.34 kb mouse albumin enhancer/promoter (M. Magnuson verified mouse promoter, personal communication), a nuclear localization sequence-modified Cre recombinase gene and a 2.1 kb fragment from the human growth hormone gene. The promoter is active in hepatocyte cells of the liver. 7 copies of the transgene are estimated to be present. Line 21 inserted into the gene at 3172116-3172120 (Build GRCm38/mm10) resulting in a 4 bp deletion. Founder line x has a copy number of approximately 10.
Find mice (IMSR): Mouse Strains: 6 strains available       Cell Lines: 0 lines available
Tissue Information
Liver & Biliary System Other recombinase alleles with activity in Liver & Biliary System tissues:
Images
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J:193672 Full Image
Fig. Alb Liver 2 E15.5
J:193672 Full Image
Fig. Alb Liver E15.5
J:193672 Full Image
Fig. Alb Liver P56
J:193672 Full Image
Fig. Alb Liver P7
J:51826 Fig. 4
Recombinase Activity
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Assays Genotypic Background Result Notes  
References
All for this allele: 1456 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory