Speer6-ps1<Tg(Alb-cre)21Mgn> - Cardiovascular System Recombinase Activity Detail MGI Mouse

Speer6-ps1^{Tg(Alb-cre)21Mgn} - Cardiovascular System
Recombinase Activity Detail

Allele Information | Recombinase Activity | References

Allele Information

Allele:

Speer6-ps1^{Tg(Alb-cre)21Mgn}
spermatogenesis associated glutamate (E)-rich protein 6, pseudogene 1; transgene insertion 21, Mark A Magnuson

Driver: Alb
Type: Transgenic (Recombinase)

Synonym:

Alb^cre, Alb-cre, AlbCre, Alb-Cre, Alb^cre2, albumin-cre, cr^Alb, Cre^ALB, Tg(Alb-cre)21Mg

Molecular description:

The transgene contains a 2.34 kb mouse albumin enhancer/promoter (M. Magnuson verified mouse promoter, personal communication), a nuclear localization sequence-modified Cre recombinase gene and a 2.1 kb fragment from the human growth hormone gene. The promoter is active in hepatocyte cells of the liver. 7 copies of the transgene are estimated to be present. Line 21 inserted into the gene at 3172116-3172120 (Build GRCm38/mm10) resulting in a 4 bp deletion. Founder line x has a copy number of approximately 10.

Find mice (IMSR):

Mouse Strains: 6 strains available Cell Lines: 0 lines available

Additional Tissues:

Speer6-ps1^{Tg(Alb-cre)21Mgn} activity also observed in:
liver & biliary system

Recombinase Activity

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Assays Genotypic Background Result Notes

References

All for this allele:

1455 reference(s)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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