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Tg(Nes-cre)1Kln - Nervous System
Recombinase Activity Detail
Allele Information
transgene insertion 1, Rudiger Klein
Driver: Nes
Type: Transgenic (Recombinase)
Synonym: n-Cre+, Nes11Cre, NesCre, nestin-Cre, nestin/Cre, Nestin:Cre, Tg(Nes-cre), TgN(NesCre)1Kln
Molecular description: This transgene expresses Cre recombinase with a human growth hormone polyadenylation signal under the control of a rat nestin (Nes) promoter and the nervous system-specific enhancer present in the second intron. This promoter expresses Cre recombinase in neuronal and glial cell precursor. Cre recombinase activity is present in nervous tissue by embryonic day 11. The transgene was localized to chromosome 12 using FISH with a rat nestin promoter probe (J:180046).
Find mice (IMSR): Mouse Strains: 3 strains available       Cell Lines: 0 lines available
Additional Tissues: Tg(Nes-cre)1Kln activity also observed in:
Tissue Information
Nervous System Other recombinase alleles with activity in Nervous System tissues:
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J:108509 Fig. S2 J:137251 Fig. 2 J:137251 Fig. 4 J:137251 Fig. 6 J:137251 Fig. S2 J:137251 Fig. S3 J:184578 Full image
Fig. Nes Brain P56
J:184578 Full image
Fig. Nes Brain P7
J:184578 Full image
Fig. Nes Embryo 2 E10.5
J:184578 Full image
Fig. Nes Embryo 2 E15.5
J:184578 Full image
Fig. Nes Embryo E10.5
J:184578 Full image
Fig. Nes Embryo E15.5
J:99607 Fig. 3
Recombinase Activity
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Assays Genotypic Background Result Notes  
All for this allele: 635 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.03
The Jackson Laboratory