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Tg(Nes-cre)1Kln - Muscle
Recombinase Activity Detail
Allele Information
Allele:
Tg(Nes-cre)1Kln
transgene insertion 1, Rudiger Klein
Driver: Nes
Type: Transgenic (Recombinase)
Synonym: n-Cre+, Nes11Cre, NesCre, nestin-Cre, nestin/Cre, Nestin:Cre, Tg(Nes-cre)
Molecular description: This transgene expresses Cre recombinase with a human growth hormone polyadenylation signal under the control of a rat nestin (Nes) promoter and the nervous system-specific enhancer present in the second intron. This promoter expresses Cre recombinase in neuronal and glial cell precursor. Cre recombinase activity is present in nervous tissue by embryonic day 11. The transgene was localized to chromosome 12 using FISH with a rat nestin promoter probe (J:180046).
Find mice (IMSR): Mouse Strains: 4 strains available       Cell Lines: 0 lines available
Additional Tissues: Tg(Nes-cre)1Kln activity also observed in:
Tissue Information
Muscle Other recombinase alleles with activity in Muscle tissues:
Images
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J:184578 Full image
Fig. Nes Embryo 2 E15.5
J:184578 Full image
Fig. Nes Embryo E15.5
J:184578 Full image
Fig. Nes Skel Muscle P56
J:184578 Full image
Fig. Nes Skel Muscle P7
Recombinase Activity
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Assays Genotypic Background Result Notes  
References
All for this allele: 524 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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Funding Information
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last database update
07/15/2014
MGI 5.18
The Jackson Laboratory