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Allele Information
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Allele:
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Tg(MMTV-cre)4Mam
transgene insertion 4, Lothar Hennighausen
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Driver: MMTV
Type: Transgenic (Cre/Flp)
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Synonym:
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CreD, Line D, MMTV-Cre, MMTV-CreD, D-line, MMTV-CreNLST
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Molecular description:
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This transgene directs the expression of Cre recombinase under the control of the mouse mammary tumor virus (MMTV) long terminal repeat. The viral MMTV promoter directed expression of Cre recombinase in the secretory epithelium of the mammary gland, the salivary gland, seminal vesicle, skin, erythrocytes, B and T cells. This line does not express cre in oocytes.
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Find mice (IMSR):
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Mouse Strains:
1 lines available
Cell Lines:
0 lines available
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Additional Tissues:
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Tg(MMTV-cre)4Mam activity also observed in:
alimentary system,
cardiovascular system,
embryo-other,
endocrine system,
integumental system,
liver and biliary system,
nervous system,
renal and urinary system,
reproductive system,
respiratory system,
sensory organs
(less)
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Tissue Information
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Hemolymphoid System
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Other recombinase alleles with activity in Hemolymphoid System tissues:
Airetm3(cre)Mmat,
Calb2tm1(cre)Zjh,
Ccktm1.1(cre)Zjh,
Cd19tm1(cre)Cgn,
Crhtm1(cre)Zjh,
Emx1tm1(cre)Krj,
Fgf16tm1.1(cre)Sms,
Foxn1tm3(cre)Nrm,
Gja10tm2.1(cre)Kwi,
Gt(ROSA)26Sortm1.1(cre)Jphe,
Gt(ROSA)26Sortm1(cre/ERT2)Tyj,
Gt(ROSA)26Sortm2(icre/ERT2)Jphe,
Hprttm1(cre)Mnn,
Ighg1tm1(IRES-cre)Cgn,
Lyz2tm1(cre)Ifo,
Mcm2tm1(cre/ERT2)Scpr,
Mnx1tm4(cre)Tmj,
Myf5tm3(cre)Sor,
Neurod6tm1(cre)Kan,
Pax3tm1(cre)Joe,
Pvalbtm1(cre)Arbr,
Shhtm1(EGFP/cre)Cjt,
Slc6a3tm1.1(cre)Bkmn,
Sox17tm1(icre)Heli,
Tg(Acp5-cre)3Rda,
Tg(ACTB-cre)1Tes,
Tg(Aicda-cre)9Mbu,
Tg(Aire-cre)1Mnt,
Tg(Aire-cre)410-5Mmat,
Tg(CD2-cre)4Kio,
Tg(Cdh5-cre)1Nmoc,
Tg(Cdh5-cre)7Mlia,
Tg(Cdh5-cre/ERT2)CIVE23Mlia,
Tg(Chst4-cre)1Hkwa,
Tg(Cma1-cre)6Thhe,
Tg(CMV-cre)1Cgn,
Tg(CMV-cre)1Nagy,
Tg(Col1a2-cre)23Angl,
Tg(Cr2-cre)3Cgn,
Tg(Csf1r-icre)1Jwp,
Tg(Cyp17a1-cre)ACmk,
Tg(EIIa-cre)C5379Lmgd,
Tg(Fabp4-cre)1Rev,
Tg(Gata1-cre)1Sho,
Tg(GFAP-cre)25Mes,
Tg(Grik4-cre)G32-4Stl,
Tg(GZMB-cre)1Jcb,
Tg(H2-Ead-cre)158Jcb,
Tg(HBB-cre)12Kpe,
Tg(HBB-cre)27038Kpe,
Tg(HBB-cre)27053Kpe,
Tg(Hoxb7-cre)13Amc,
Tg(Hspa2-cre)1Eddy,
Tg(Il7-cre)CRche,
Tg(Itga2b-cre)AParl,
Tg(Itga2b-cre)NE1/21Emam,
Tg(ITGAM-cre)2781Gkl,
Tg(Itgax-cre)1-1Reiz,
Tg(Kdr-cre)15962Brei,
Tg(KRT14-cre)1Amc,
Tg(KRT14-cre)1Cgn,
Tg(KRT14-cre)8Brn,
Tg(KRT5-cre/ERT)ICmch,
Tg(KRT5-cre/ERT)SCmch,
Tg(Lck-cre)548Jxm,
Tg(MMTV-cre)1Mam,
Tg(Mx1-cre)29-4Her,
Tg(Myh11-cre/ERT2)1Soff,
Tg(Nes-cre)1Atp,
Tg(Nes-cre)1Kln,
Tg(Neurog3-cre)C1Able,
Tg(Nr5a1-cre)2Klp,
Tg(Nr5a1-cre)2Lowl,
Tg(Pcp2-cre)1Amc,
Tg(Pdgfb-icre/ERT2)1Frut,
Tg(Pf4-cre)Q3Rsko,
Tg(Plp1-cre/ERT)3Pop,
Tg(Sim1-cre)1Lowl,
Tg(Sox10-cre)1Wdr,
Tg(Tagln-cre)1Her,
Tg(Tek-cre)12Flv,
Tg(Tek-cre)1Arnd,
Tg(Tek-cre)5326Sato,
Tg(Tek-cre/ERT2)1Arnd,
Tg(Tek-cre/ERT2)1Soff,
Tg(Thy1-cre)1Vln,
Tg(Vav1-cre)1Cgp,
Tg(Vav1-cre)1Graf,
Tg(Vav1-cre)8Cgp,
Tg(Vav1-cre)A2Kio,
Tg(Wfs1-cre/ERT2)3Aibs,
Tg(Wnt1-cre)11Rth,
Tg(Zp3-cre)3Mrt,
Twist2tm1.1(cre)Dor
(less)
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Images
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Reset Images
J:193672
Fig. MMTV Bone P7
J:193672
Fig. MMTV Lymph Node Adult
J:193672
Fig. MMTV Spleen Adult
J:193672
Fig. MMTV Spleen P7
J:193672
Fig. MMTV Thymus Adult
J:193672
Fig. MMTV Thymus E15.5
J:193672
Fig. MMTV Thymus P7
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Recombinase Activity
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Click heading to resort table.
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References
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Analysis Tools