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Allele Information
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Allele:
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Tg(Mx1-cre)1Cgn
transgene insertion 1, University of Cologne
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Driver: Mx1
Type: Transgenic (Cre/Flp)
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Inducer:
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Induced by interferon (-alpha or -beta) or polyinosinic-polycytidylic acid (pI:pC).
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Synonym:
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Mx1cre, Mx-Cre 31, MxCreTg, MxCre, Mx-Cre, Mx1-Cre
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Molecular description:
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This transgene expresses Cre recombinase under the control of an inducible Mx1 promoter, which is silent in healthy mice, and active in the liver and in lymphocytes after induction with IFN or pI-pC. The construct also contains a 2.1 kb fragment from the human growth hormone gene.
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Find mice (IMSR):
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Mouse Strains:
6 lines available
Cell Lines:
0 lines available
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Additional Tissues:
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Tg(Mx1-cre)1Cgn activity also observed in:
alimentary system,
cardiovascular system,
endocrine system,
integumental system,
renal and urinary system
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Tissue Information
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Liver And Biliary System
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Other recombinase alleles with activity in Liver And Biliary System tissues:
Albtm1(cre/ERT2)Mtz,
Calb2tm1(cre)Zjh,
Ccktm1.1(cre)Zjh,
Cldn6tm1(cre/ERT2)Dam,
Eportm1(EGFP/cre)Uk,
Gad2tm2(cre)Zjh,
Gt(ROSA)26Sortm1.1(cre)Jphe,
Gt(ROSA)26Sortm1(cre/ERT2)Tyj,
Gt(ROSA)26Sortm1(cre/ERT)Brn,
Gt(ROSA)26Sortm2(cre/ERT2)Brn,
Gt(ROSA)26Sortm2(icre/ERT2)Jphe,
Hnf4atm1(cre)Sdv,
Hprttm1(cre)Mnn,
Krt19tm1(cre/ERT)Ggu,
Lyz2tm1(cre)Ifo,
Myf5tm3(cre)Sor,
Nkx2-5tm2(cre)Rph,
Ptf1atm1.1(cre)Cvw,
Runx1tm1(cre/Esr1*)Ims,
Shhtm1(EGFP/cre)Cjt,
Sox17tm1(icre)Heli,
Sox17tm2.1(icre)Heli,
Taglntm2(cre)Yec,
Tg(Acp5-cre)3Rda,
Tg(Acp5-cre)4Rda,
Tg(ACTB-cre)1Tes,
Tg(Acvrl1-cre)B1Spo,
Tg(Alb1-cre)1Dlr,
Tg(Alb1-cre)1Khk,
Tg(Alb1-cre)7Gsc,
Tg(Alb-cre)21Mgn,
Tg(Amy2-cre)1Herr,
Tg(CAG-cre/Esr1*)1Lbe,
Tg(CAG-cre/Esr1*)5Amc,
Tg(CAG-cre/Esr1*)86Lbgn,
Tg(Car1-cre)5Flt,
Tg(CD2-cre)4Kio,
Tg(Cdh5-cre)1Nmoc,
Tg(Cdh5-cre)1Spe,
Tg(Cdh5-cre)7Mlia,
Tg(Cdh5-cre/ERT2)CIVE23Mlia,
Tg(Chst4-cre)1Hkwa,
Tg(CMV-cre)1Cgn,
Tg(Col1a2-cre)23Angl,
Tg(Csf1r-icre)1Jwp,
Tg(Ctsk-cre)8Rda,
Tg(Cyp17a1-cre)ACmk,
Tg(Cyp19a1-cre)5909Gle,
Tg(Cyp1a1-cre)1Dwi,
Tg(Cyp1a1-cre/ERT)1Dwi,
Tg(EIIa-cre)C5379Lmgd,
Tg(Fabp1-cre)1Jig,
Tg(Fabp4-cre)1Rev,
Tg(Gata1-cre)1Sho,
Tg(GATA5-cre)1Krc,
Tg(GFAP-cre)25Mes,
Tg(Grik4-cre)G32-4Stl,
Tg(HBB-cre)12Kpe,
Tg(HBB-cre)27038Kpe,
Tg(HBB-cre)27053Kpe,
Tg(Hspa2-cre)1Eddy,
Tg(Il7-cre)CRche,
Tg(Ins2-cre)25Mgn,
Tg(Itga2b-cre)AParl,
Tg(Itga2b-cre)NE1/21Emam,
Tg(Itgax-cre)1-1Reiz,
Tg(Kap-cre)29066/2Sig,
Tg(Kdr-cre)15962Brei,
Tg(KRT14-cre)1Amc,
Tg(KRT18-cre/ERT2)1Rgo,
Tg(MMTV-cre)4Mam,
Tg(Mx1-cre)29-4Her,
Tg(MYOD1-cre)M23Glh,
Tg(Nes-cre)1Atp,
Tg(Nes-cre)1Kln,
Tg(Nkx2-5-cre)9Eno,
Tg(Pcp2-cre)1Amc,
Tg(Pcp2-cre)2Mpin,
Tg(Pdgfb-icre/ERT2)1Frut,
Tg(Pf4-cre)Q3Rsko,
Tg(REN-cre)1Haca,
Tg(SERPINA1-cre)1Arge,
Tg(SERPINA1-cre/ERT)1Ipc,
Tg(Sim1-cre)1Lowl,
Tg(Tagln-cre)1Her,
Tg(Tagln-cre)1Jjl,
Tg(Tal1-cre/ERT)1Jrg,
Tg(Tal1-cre/ERT)42-056Jrg,
Tg(Tek-cre)1Arnd,
Tg(Tek-cre)5326Sato,
Tg(Tek-cre/ERT2)1Arnd,
Tg(Tek-cre/ERT2)1Soff,
Tg(tetO-cre)LC1Bjd,
Tg(Thy1-cre)1Vln,
Tg(Thy1-cre)703Vaw,
Tg(Tie1-cre)9Ref,
Tg(Ttr-cre/Esr1*)1Vco,
Tg(UBC-cre/ERT2)1Ejb,
Tg(Vav1-cre)1Graf,
Tg(Wfs1-cre/ERT2)3Aibs,
Tg(Wnt1-cre)11Rth,
Tg(Zp3-cre)3Mrt,
Twist2tm1.1(cre)Dor
(less)
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Images
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J:143936
Fig. 1
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Recombinase Activity
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Click heading to resort table.
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References
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Analysis Tools