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Tg(Mx1-cre)1Cgn - Cardiovascular System
Recombinase Activity Detail
Allele Information
Allele:
Tg(Mx1-cre)1Cgn
transgene insertion 1, University of Cologne
Driver: Mx1
Type: Transgenic (Cre/Flp)
Inducer: Induced by interferon (-alpha or -beta) or polyinosinic-polycytidylic acid (pI:pC).
Synonym: Mx1cre, Mx1-Cre, MxCre, Mx-Cre, Mx-Cre 31, MxCreTg
Molecular description: This transgene expresses Cre recombinase under the control of an inducible Mx1 promoter, which is silent in healthy mice, and active in the liver and in lymphocytes after induction with IFN or pI-pC. The construct also contains a 2.1 kb fragment from the human growth hormone gene.
Find mice (IMSR): Mouse Strains: 6 lines available       Cell Lines: 0 lines available
Additional Tissues: Tg(Mx1-cre)1Cgn activity also observed in:
Tissue Information
Cardiovascular System Other recombinase alleles with activity in Cardiovascular System tissues:
Images
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J:193672 Full image
Fig. Mx1 Heart P56
Recombinase Activity
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Assays Genotypic Background Result Notes  
References
All for this allele: 646 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
04/08/2014
MGI 5.17
The Jackson Laboratory