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Allele Information
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Allele:
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Tg(EIIa-cre)C5379Lmgd
transgene insertion C5379, Laboratory of Mammalian Genes and Development, Heiner Westphal
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Driver: EIIa
Type: Transgenic (Cre/Flp)
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Synonym:
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EIIaCre, Ela-Cre, EIIa-cre, TgN(EIIa-Cre)C5379Lmgd, EIIaCre deleter, EII-cre, EIIa Cretg, E2a-Cre
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Molecular description:
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The adenovirus EIIa promoter directs expression of Cre recombinase in preimplantation mouse embryos. This transgene expresses Cre recombinase in nearly all tissues.
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Find mice (IMSR):
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Mouse Strains:
4 lines available
Cell Lines:
0 lines available
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Additional Tissues:
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Tg(EIIa-cre)C5379Lmgd activity also observed in:
adipose tissue,
alimentary system,
branchial arches,
cardiovascular system,
cavities and their linings,
endocrine system,
extraembryonic component,
head,
hemolymphoid system,
integumental system,
limbs,
liver and biliary system,
mesenchyme,
muscle,
nervous system,
postnatal-other,
renal and urinary system,
reproductive system,
respiratory system,
sensory organs,
skeletal system,
tail
(less)
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Tissue Information
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Embryo-other
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Other recombinase alleles with activity in Embryo-other tissues:
1700009P17Riktm1.1(icre)Heli,
Acantm1(cre/ERT2)Crm,
Alpltm1(cre)Nagy,
Bmpr1bTg(ACTB-FLP)4917Dym,
Calb2tm1(cre)Zjh,
Cldn6tm1(cre/ERT2)Dam,
Fgf16tm1.1(cre)Sms,
Foxa2tm2.1(cre/Esr1*)Moon,
Foxg1tm1(cre)Skm,
Gt(ROSA)26Sortm1.1(rtTA,tetO-cre)Bkmn,
Gt(ROSA)26Sortm1(FLP1)Dym,
Gt(ROSA)26Sortm2(cre/ERT2)Brn,
Gt(ROSA)26Sortm3(phiC31*)Sor,
Gt(ROSA)26Sortm5(phiC31)Sor,
HhatTg(TFAP2A-cre)1Will,
Hoxa3tm1(cre)Moon,
Hprttm10(Ple162-EGFP/cre)Ems,
Hprttm1(cre)Mnn,
Kdrtm1(cre)Sato,
Krt19tm1(cre)Mmt,
Mapttm1(cre)Nagy,
Meox2tm1(cre)Sor,
Mesp1tm2(cre)Ysa,
Mnx1tm4(cre)Tmj,
Myf5tm1.1(cre)Mrc,
Myf5tm1(cre)Mrc,
Myf5tm3(cre)Sor,
Myf6tm1(cre)Mrc,
Myf6tm2(cre)Mrc,
Myocdtm1(cre)Jomm,
Myod1tm2.1(icre)Glh,
Nkx2-5tm1(cre)Rjs,
Nkx3-2tm3.1(cre)Tlu,
Nkx3-2tm4.1(cre)Tlu,
Notch1tm3(cre)Rko,
Osr1tm1(EGFP/cre/ERT2)Amc,
Osr2tm2(cre)Jian,
Pax3tm1(cre)Joe,
Pax7tm1(cre)Mrc,
Runx1tm1(cre/Esr1*)Ims,
Runx1tm2.1(cre/Esr1*)Ims,
Shhtm1(EGFP/cre)Cjt,
Six1tm1(cre,ALPP)Xli,
Sox17tm2.1(icre)Heli,
Ssttm2.1(cre)Zjh,
Taglntm2(cre)Yec,
Tfap2atm1(cre)Moon,
Tg(ACTA1-cre)1Mll,
Tg(ACTA1-cre)79Jme,
Tg(ACTA1-rtTA,tetO-cre)102Monk,
Tg(ACTB-cre)2Mrt,
Tg(ACTC1-cre)1Miwa,
Tg(ACTFLPe)9205Dym,
Tg(Acvrl1-cre)B1Spo,
Tg(Acvrl1-cre)L1Spo,
Tg(CAG-cre)13Miya,
Tg(CAG-cre)1Nagy,
Tg(CAG-cre)2Osb,
Tg(CAG-cre/Esr1*)1Lbe,
Tg(CAG-cre/Esr1*)5Amc,
Tg(CAG-dre)1Afst,
Tg(CAG-Flpo)1Afst,
Tg(Camk2a-cre)1Nobs,
Tg(Cdh5-cre/ERT2)CIVE23Mlia,
Tg(Cdx1-cre)23Kem,
Tg(CDX2-cre)101Erf,
Tg(Cga-cre)3Sac,
Tg(CMV-cre)1And,
Tg(CMV-cre)1Cgn,
Tg(Col10a1-cre)1Xya,
Tg(Col11a2-cre)4Nhzi,
Tg(Col1a1-cre)1Kry,
Tg(Col1a1-cre/Esr1*)1Mis,
Tg(Col1a1-cre)#Xya,
Tg(Col1a2-cre)23Angl,
Tg(Col2a1-cre)10Amc,
Tg(Col2a1-cre)15Amc,
Tg(Col2a1-cre)1Asz,
Tg(Col2a1-cre)1Bhr,
Tg(Col2a1-cre)1Rsjo,
Tg(COL2A1-cre)1Wag,
Tg(Col2a1-cre)3Amc,
Tg(Col2a1-cre/ERT)1Flng,
Tg(Col2a1-cre/ERT)KA3Smac,
Tg(Col2a1-rtTA,tetO-cre)22Pjro,
Tg(Cryaa-cre)39Mlr,
Tg(Cyp19a1-cre)5909Gle,
Tg(Cyp19a1-cre)5912Gle,
Tg(Dct-cre)1Apdn,
Tg(Dll1-cre)33Dchp,
Tg(dlx6a-cre)1Mekk,
Tg(DMRT1-cre)1Svs,
Tg(Emx1-cre)3Ito,
Tgfb3tm1(cre)Vk,
Tg(Fgf15-cre)1Bld,
Tg(Fgf15/Hsp68-cre)1Bld,
Tg(Foxa2*-cre)#Mku,
Tg(Frzb-cre)1Tylz,
Tg(Frzb-cre)2Tylz,
Tg(Frzb-cre)3Tylz,
Tg(Fzd10-cre/Esr1*)1Chzh,
Tg(Gata1-cre)1Sho,
Tg(GATA5-cre)1Krc,
Tg(Grik4-cre)G32-4Stl,
Tg(Hand2-cre)7-1Clou,
Tg(HBB-cre)12Kpe,
Tg(HBB-cre)27038Kpe,
Tg(HBB-cre)27053Kpe,
Tg(Hes7-cre)1Kag,
Tg(Hhex-cre,-GFP)1Ksz,
Tg(Hoxa1-cre)1Tlu,
Tg(Hoxb6-cre)C33Mku,
Tg(Hoxb6-cre/ERT)1Smac,
Tg(Hoxb7-cre)13Amc,
Tg(Hoxb8-cre)1403Uze,
Tg(Hspa2-cre)1Eddy,
Tg(Htr1a-icre)1Fto,
Tg(Itga2b-cre)NE1/21Emam,
Tg(Kdr-cre)15962Brei,
Tg(Kera-cre)KC4.3Wwk,
Tg(Lck-cre)548Jxm,
Tg(Leftb-cre)1Hmd,
Tg(Mef2c-cre)1Blk,
Tg(mI56i-cre)6-2Clou,
Tg(Mitf-cre)7114Gsb,
Tg(MMTV-cre)4Mam,
Tg(Mpz-cre)94Imeg,
Tg(Myh7-cre)1Zli,
Tg(Myl1-cre)13Nros,
Tg(myl2-cre)1118Tmhn,
Tg(myl2-cre)1141Tmhn,
Tg(MYOD1-cre)M23Glh,
Tg(Myog-cre)1Eno,
Tg(Nes-cre)1Atp,
Tg(Nes-cre)1Wme,
Tg(Neurog3-cre)C1Able,
Tg(Nodal-cre)16Hmd,
Tg(Nodal-cre)1Rob,
Tg(Nodal*-cre)#Mku,
Tg(Nppa-cre)3Vmc,
Tg(Nr5a1-cre)1Kmor,
Tg(Nr5a1-cre)2Klp,
Tg(Pax2-cre)10Shwl,
Tg(Pax2-cre)1Akg,
Tg(Pax3-cre)1Joe,
Tg(Pax3-cre)2Joe,
Tg(Pax6-cre,GFP)1Pgr,
Tg(Pcp2-cre)1Amc,
Tg(Pcp2-cre)2Mpin,
Tg(Pitx3-cre/ERT2)1Ydq,
Tg(Pou3f4-cre)32Cren,
Tg(Prdm1-cre)1Masu,
Tg(Prrx1-cre)1Cjt,
Tg(Rarb-cre)1Bhr,
Tg(REN-cre)1Haca,
Tg(Scx-cre)HShuk,
Tg(Sftpa1-cre)1Xya,
Tg(Slc17a6-icre)1Oki,
Tg(Smad7-cre)1Sjc,
Tg(Sox10-cre)1Wdr,
Tg(Sox10-cre)507Mcln,
Tg(Sox2-cre)1Amc,
Tg(Sp7-tTA,tetO-EGFP/cre)1Amc,
Tg(Tagln-cre)1Her,
Tg(Tal1-cre/ERT)42-056Jrg,
Tg(T-cre)1Gos,
Tg(T-cre)1Lwd,
Tg(Tek-cre)5326Sato,
Tg(Tek-cre)#Xya,
Tg(Thy1-cre)1Vln,
Tg(Tie1-cre)9Ref,
Tg(Tlx2-cre)#Mori,
Tg(TSPY-cre)33aYfcl,
Tg(Tyr-cre)1Gfk,
Tg(Tyr-cre)1Lru,
Tg(Tyr-cre/ERT2)1Laru,
Tg(Tyrp1-cre)1Ipc,
Tg(Ure2-cre)1Jlr,
Tg(Vav1-cre)8Cgp,
Tg(Wnt1-cre)11Rth,
Tg(WT1-cre)1Asc,
Tg(WT1-cre)AG11Dbdr,
Tg(Zp3-cre)3Mrt,
Twist2tm1.1(cre)Dor,
Twist2tm1(cre)Dor
(less)
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Images
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J:137251
Fig. 2
J:137887
Fig. EIIa Embryo 1 E10.5
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Fig. EIIa Embryo 2 E10.5
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Fig. EIIa Embryo 2 E15.5
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Fig. EIIa Embryo a E10.5
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Fig. EIIa Embryo a E15.5
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Fig. EIIa Embryo b E10.5
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Fig. EIIa Embryo b E15.5
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Fig. EIIa Embryo caudal E15.5
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Fig. EIIa Embryo c E10.5
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Fig. EIIa Embryo d E10.5
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Fig. EIIa Embyo 3 E15.5
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Fig. EIIa Embryo 2 E10.5
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Fig. EIIa Embryo E10.5
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Recombinase Activity
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Click heading to resort table.
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References
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Analysis Tools