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Tg(Tek-cre)12Flv - Cardiovascular System
Recombinase Activity Detail
Allele Information
Allele:
Tg(Tek-cre)12Flv
transgene insertion 12, Richard A Flavell 		Driver: Tek
Type: Transgenic (Cre/Flp)
Synonym: Tie2-Cre, Tet-cre, TIE2Cre+, btie2-cre, Tie2-Cre, TIE2/cre, Tie2(Tek)-Cre, TIE2Cre, CreTek, Tek-Cre
Molecular description: Cre recombinase expression is driven by a mouse endothelial-specific receptor tyrosine kinase promoter/enhancer. Recombinase activity is detected in endothelial cells during embryogenesis and adulthood. Expression was also detected in hematopoietic cells. The promoter has also been reported to be active in female germ cells. A low frequency of deletion events are also observed by inheritance from the male germline.
Find mice (IMSR): Mouse Strains: 1 lines available       Cell Lines: 0 lines available
Additional Tissues: Tg(Tek-cre)12Flv activity also observed in:
alimentary system, hemolymphoid system
Tissue Information
Cardiovascular System Other recombinase alleles with activity in Cardiovascular System tissues:
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J:68147
Fig. 3
Recombinase Activity
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Assays Genotypic Background Result Notes  
References
All for this allele: 158 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
05/22/2013
MGI 5.13 		The Jackson Laboratory