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Emx1tm1(cre)Ito - Nervous System
Recombinase Activity Detail
Allele Information
Allele:
Emx1tm1(cre)Ito
empty spiracles homeobox 1; targeted mutation 1, Shigeyoshi Itohara 		Driver: Emx1
Type: Targeted (Recombinase)
Synonym: Emx1Cre, (Emx1)Cre, Emx1Cre, Emx1-Cre, Emx1tm1(cre)Rik
Molecular description: A cDNA encoding cre recombinase with an N-terminal nuclear localization signal (nls) was inserted immediately before the translation initiation codon in the gene. Under the control of this promoter, Cre activity is detected by embryonic day 12.5; Cre mediated recombination was observed in dorsal telencephalon, neocortex, hippocampus, and olfactory bulb. An Frt flanked Neo cassette was retained in this allele
Find mice (IMSR): Mouse Strains: 1 strain available       Cell Lines: 0 lines available
Additional Tissues: Emx1tm1(cre)Ito activity also observed in:
head
Tissue Information
Nervous System Other recombinase alleles with activity in Nervous System tissues:
Images
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J:88421 Fig. 2 J:88421 Fig. 5 J:88421 Fig. 7
Recombinase Activity
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Assays Genotypic Background Result Notes  
References
All for this allele: 99 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory