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pJ11 Probe Detail
Nucleotide
Probe/Clone
  • Name
    pJ11
  • Sequence Type
    genomic
  • ID
    MGI:12035
  • Region Covered
    encodes 3' flanking sequences and two Igh-J gene segments (J3 and J4)
  • Parent Clone
  • Vector Type
    Plasmid
  • Insert Site
    EcoRI/BamHI
  • Insert Size
    ~1.7kb
  • Synonyms
    J11, J>11<, M23(J11)
Source
  • Species
    mouse, laboratory
  • Strain
    BALB/cJ
  • Tissue
    liver
Genes
Igh-J immunoglobulin heavy chain, joining region
Polymorphisms
J:11471 Moore SK, et al., Genomics. 1991 Aug;10(4):1019-29
Endonuclease Gene Allele Fragments Strains
BglII Igh-J m not given M. m. musculus
n not given AKR/J, C58/J, NFS/N
References
J:6394 Marcu KB, et al., 5' flanking region of immunoglobulin heavy chain constant region genes displays length heterogeneity in germlines of inbred mouse strains. Cell. 1980 Nov;22(1 Pt 1):187-96
J:6721 Lang RB, et al., On immunoglobulin heavy chain gene switching: two gamma 2b genes are rearranged via switch sequences in MPC-11 cells but only one is expressed. Nucleic Acids Res. 1982 Jan 22;10(2):611-30
J:7830 Eckhardt LA, et al., Independent immunoglobulin class-switch events occurring in a single myeloma cell line. Mol Cell Biol. 1985 Apr;5(4):856-68
J:8641 Brown EH, et al., Rate of replication of the murine immunoglobulin heavy-chain locus: evidence that the region is part of a single replicon. Mol Cell Biol. 1987 Jan;7(1):450-7
J:8764 Gilmore GL, et al., Absence of somatic mutation in the variable region of MPC 11 variants expressing a different heavy chain isotype. J Immunol. 1987 Jul 15;139(2):619-24
J:20304 Vasmel WL, et al., Refinement and precision in the classification of murine lymphomas by genotyping with immunoglobulin and T cell receptor probes. Leukemia. 1987 Mar;1(3):155-62
J:11471 Moore SK, et al., Mapping of the mouse 86-kDa heat-shock protein expressed gene (Hsp86-1) on chromosome 12 and related genes on chromosomes 3, 4, 9, and 11. Genomics. 1991 Aug;10(4):1019-29
J:30855 Mainville CA, et al., Deletional mapping of fifteen mouse VH gene families reveals a common organization for three Igh haplotypes. J Immunol. 1996 Feb 1;156(3):1038-46

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory