1-1 |
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Recipients of awards for pioneering the development of inbred mouse strains. |
1-2 |
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Dr. William Ernest Castle. |
1-3 |
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The Bussey Institute of Harvard University. |
1-4 |
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W.E. Castle's intellectual family tree. |
1-5 |
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Miss Abbie E.C. Lathrop. |
1-6 |
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W.E. Castle's acknowledgement to Michael Potter that mice used at the Bussey were obtained from Abbie Lathrop. |
1-7 |
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A page from Miss Lathrop's breeding records. |
1-8 |
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Reports prepared by Miss Lathrop. |
1-9 |
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The Granby Mouse Farm. |
1-10 |
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The genealogy of inbred mice. |
5-1 |
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Clarence C. Little. |
6-1 |
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Distribution of Strong inbred mice to laboratories where colonies were established. |
6-2 |
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Incidence of methylcholanthrene-induced fibrosarcomas in 15 strains of inbred mice. |
6-3 |
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Leonell C. Strong. |
7-1 |
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The effect of thymectomy on the incidence of leukemia and on longevity. |
7-2 |
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Inhibition of development of leukemia with increase of life span by underfeeding. |
7-3 |
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Appearance of epithelial-reticular cell cultures of the thymus at different magnifications. |
7-4 |
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Sculpture of Ak mice crawling over bookends. |
7-5 |
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Jacob Furth. |
8-1 |
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Howard B. Andervont. |
10-1 |
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Walter E. Heston. |
11-1 |
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The cross-intercross or M system of producing congenic resistant strains. |
11-2 |
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The cross-backcross-intercross or N system of producing congenic resistant strains. |
11-3 |
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George D. Snell. |
12-1 |
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Margaret C. Green. |
13-1 |
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Earl L. Green. |
14-1 |
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Clyde Keeler. |
15-1 |
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The probability of no heterogenic tract remaining after the indicated number of generations of full-sib mating in mice. |
15-2 |
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The number of fixed gene differences expected between hypothetical sublines relative to the generation at which they branched. |
15-3 |
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An equivalence curve that allows comparison of the relative importance of mutation and residual heterozygosity as sources of subline divergence. |
15-4 |
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Diagrams of subline derivations in six major inbred strains in mice. |
16-1 |
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Origin of some of the inbred strains and substrains of mice maintained at the National Institutes of Health. |
16-2 |
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Linkage map of the laboratory mouse of genetic markers used for the genetic profile. |
17-1 |
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Chromosomal location of genes specifying the structure of proteins. |
17-2 |
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Electrophoretic forms of glutamate oxaloacetate transaminases. |
17-3 |
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Genetic maps of a segment of mouse chromosome 7. |
17-4 |
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Electrophoretic patterns of glucose phosphate isomerase (GPI-1) from cells and mixtures of cells of differing genotype at Gpi-1. |
17-5 |
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Isozymes of glucose phosphate isomerase found in embryos of various ages. |
21-1 |
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Genome and structural components of type-C murine leukemia viruses. |
21-2 |
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SDS-polyacrylamide gele electrophoresis analysis of iodinated xenotropic MuLV. |
21-3 |
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Schematic diagram of the fluorescence activated cell sorter. |
21-4 |
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XenCSA expression by NZB thymocytes (a) and spleen cells (b) determined by flow microfluorometry (FMF). |
21-5 |
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XenCSA expression by NZB spleen cells is bimodal. |
21-6 |
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SDS-polyacrylamide gel electrophoresis analysis of molecules precipitated by anti-xenotropic MuLV antiserum. |
21-7 |
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FMF analysis of thymocytes (a, c, e) and spleen cells (b, d, f) from strains representative of the three basic patterns of XenCSA. |
21-8 |
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Mean fluorescence values of spleen cells and thymocytes from 99 strains of inbred mice. |
21-9 |
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XenCSA expression by spleen cells from C57BL/6J by DBA/2 (BXD) recombinant inbred (RI) lines. |
21-10 |
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XenCSA expression by thymocytes and spleen cells of BXD RI lines. |
23-1 |
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Competition radioimmunoassay for MMTV gp52. |
23-2 |
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Group-specific and type-specific reactivities of MMTV p28. |
23-3 |
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Tryptic peptide maps of MMTV gp52s. |
23-4 |
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Tryptic peptide maps of MMTV p28s. |
23-5 |
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Molecular hybridization of [125I]-labeled MMTV(C3H) RNA to DNA. |
23-6 |
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Kinetic analysis of hybridization between MMTV 60-70s [125I]RNA and rat cellular DNAs using relaxed conditions of hybridization and RNase assay. |
23-7 |
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Reactivity of Mus cervicolor type-B virus in MMTV gp52 and p28 radioimmunoassays. |
24-1 |
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Murine linkage map. |
24-2 |
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The median survival times (MST) of each group are plotted against the time intervals (in days) between injection of 5 x 106 thymocytes and skin grafting. |
26-1 |
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Map of the Tla region. |
26-2 |
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Chromosomes of Tla region congenic strains. |
26-3 |
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Derivation of and Qa typing for several BALB/c sublines. |
27-1 |
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Efficiency of RI strains relative to a backcross for estimation of recombination fraction. |
27-2 |
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The probability of detecting linkage using n RI strains as a function of the recombination frequency. |
29-1 |
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Numbers of mouse loci with known variants either published (early years) or listed in Mouse News Letter (later years). |
39-1 |
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The relationships of strains of the C57 group. |
39-2 |
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The relationships of strains of the DBA, BALB/c, A, and related strains. |
39-3 |
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Relationships of sublines within four unrelated groups of strains. |
40-1 |
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Agar gel electrophoresis of the nondialyzable material. |
42-1 |
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The approximate geographic limits of house mice (Mus) in western Europe and northwestern Africa. |
42-2 |
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Genetic distance (D) for samples of an inbred lab strain and native mice (Mus) from England and Spain. |
45-1 |
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Chromosomes of Mus musculus stained with quinacrine. |
45-2 |
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Chromosomes of Mus cervicolor stained with quinacrine. |
45-3 |
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Comparison of the G-band pattern of the chromosomes of a) M. musculus musculus, b) M. musculus molossinus, c) M. caroli, d) M. cervicolor,
e) m. cookii, and f) M. booduga fulvidentris. |
45-4 |
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Chromosomes of M. dunni stained with conventional Giemsa and to show C-banding. |
45-5 |
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Karyotype of M. poschiavinus (2n=26). |
45-6 |
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Meiotic cell of a (T Rov 1-6 x M. poschiavinus)F1 stained with Giemsa. |
45-7 |
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Karyotype of (musculus x molossinus)F1 stained to show C-bands. |
45-8 |
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Meiotic cell from a (musculus x molossinus)F1 stained to show C-bands. |
45-9 |
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Metaphase of Mus musculus stained to show the concentration of 5-methylcytosine in the C-band regions. |
45-10 |
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Partial karyotype of molossinus stained to show Q-bands, Ag-stained NORs and C-bands. |
45-11 |
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Karyotype of a Chinese hamster-mouse somatic hybrid cell. |
46-1 |
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Distribution of mice trapped on Great Gull Island after release of +/tw11 males in 1956 and 1957. |
47-1 |
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Correlation between the extent of cross-reactivity of anti-H-2Dd sera on human and mice cells. |
49-1 |
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The genetic map of the H-2 complex. |
49-2 |
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Distribution of 15 inbred-derived antigens among 40 wild mice from the area of Ann Arbor, Michigan. |
49-3 |
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Method used for the production of B10.W lines. |
50-1 |
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Phylogenetic tree depicting relationships among members of the family Muridae. |
50-2 |
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Competitive radioimmunoassays for P30 proteins. |
50-3 |
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Electron micrographs of virus particles from NIH/3T3 cells infected with M. cervicolor M432 and M. musculus type B (MMTV) virus from RIII tumor cells. |
50-4 |
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Competitive radioimmunoassay for M. cervicolor M432 p24 protein. |
50-5 |
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Hybridization of 3H-labeled DNA probes prepared from each of the M. cervicolor retroviruses to M. cervicolor DNA. |