Figures

1-1   Recipients of awards for pioneering the development of inbred mouse strains.
1-2   Dr. William Ernest Castle.
1-3   The Bussey Institute of Harvard University.
1-4   W.E. Castle's intellectual family tree.
1-5   Miss Abbie E.C. Lathrop.
1-6   W.E. Castle's acknowledgement to Michael Potter that mice used at the Bussey were obtained from Abbie Lathrop.
1-7   A page from Miss Lathrop's breeding records.
1-8   Reports prepared by Miss Lathrop.
1-9   The Granby Mouse Farm.
1-10   The genealogy of inbred mice.
5-1   Clarence C. Little.
6-1   Distribution of Strong inbred mice to laboratories where colonies were established.
6-2   Incidence of methylcholanthrene-induced fibrosarcomas in 15 strains of inbred mice.
6-3   Leonell C. Strong.
7-1   The effect of thymectomy on the incidence of leukemia and on longevity.
7-2   Inhibition of development of leukemia with increase of life span by underfeeding.
7-3   Appearance of epithelial-reticular cell cultures of the thymus at different magnifications.
7-4   Sculpture of Ak mice crawling over bookends.
7-5   Jacob Furth.
8-1   Howard B. Andervont.
10-1   Walter E. Heston.
11-1   The cross-intercross or M system of producing congenic resistant strains.
11-2   The cross-backcross-intercross or N system of producing congenic resistant strains.
11-3   George D. Snell.
12-1   Margaret C. Green.
13-1   Earl L. Green.
14-1   Clyde Keeler.
15-1   The probability of no heterogenic tract remaining after the indicated number of generations of full-sib mating in mice.
15-2   The number of fixed gene differences expected between hypothetical sublines relative to the generation at which they branched.
15-3   An equivalence curve that allows comparison of the relative importance of mutation and residual heterozygosity as sources of subline divergence.
15-4   Diagrams of subline derivations in six major inbred strains in mice.
16-1   Origin of some of the inbred strains and substrains of mice maintained at the National Institutes of Health.
16-2   Linkage map of the laboratory mouse of genetic markers used for the genetic profile.
17-1   Chromosomal location of genes specifying the structure of proteins.
17-2   Electrophoretic forms of glutamate oxaloacetate transaminases.
17-3   Genetic maps of a segment of mouse chromosome 7.
17-4   Electrophoretic patterns of glucose phosphate isomerase (GPI-1) from cells and mixtures of cells of differing genotype at Gpi-1.
17-5   Isozymes of glucose phosphate isomerase found in embryos of various ages.
21-1   Genome and structural components of type-C murine leukemia viruses.
21-2   SDS-polyacrylamide gele electrophoresis analysis of iodinated xenotropic MuLV.
21-3   Schematic diagram of the fluorescence activated cell sorter.
21-4   XenCSA expression by NZB thymocytes (a) and spleen cells (b) determined by flow microfluorometry (FMF).
21-5   XenCSA expression by NZB spleen cells is bimodal.
21-6   SDS-polyacrylamide gel electrophoresis analysis of molecules precipitated by anti-xenotropic MuLV antiserum.
21-7   FMF analysis of thymocytes (a, c, e) and spleen cells (b, d, f) from strains representative of the three basic patterns of XenCSA.
21-8   Mean fluorescence values of spleen cells and thymocytes from 99 strains of inbred mice.
21-9   XenCSA expression by spleen cells from C57BL/6J by DBA/2 (BXD) recombinant inbred (RI) lines.
21-10   XenCSA expression by thymocytes and spleen cells of BXD RI lines.
23-1   Competition radioimmunoassay for MMTV gp52.
23-2   Group-specific and type-specific reactivities of MMTV p28.
23-3   Tryptic peptide maps of MMTV gp52s.
23-4   Tryptic peptide maps of MMTV p28s.
23-5   Molecular hybridization of [125I]-labeled MMTV(C3H) RNA to DNA.
23-6   Kinetic analysis of hybridization between MMTV 60-70s [125I]RNA and rat cellular DNAs using relaxed conditions of hybridization and RNase assay.
23-7   Reactivity of Mus cervicolor type-B virus in MMTV gp52 and p28 radioimmunoassays.
24-1   Murine linkage map.
24-2   The median survival times (MST) of each group are plotted against the time intervals (in days) between injection of 5 x 106 thymocytes and skin grafting.
26-1   Map of the Tla region.
26-2   Chromosomes of Tla region congenic strains.
26-3   Derivation of and Qa typing for several BALB/c sublines.
27-1   Efficiency of RI strains relative to a backcross for estimation of recombination fraction.
27-2   The probability of detecting linkage using n RI strains as a function of the recombination frequency.
29-1   Numbers of mouse loci with known variants either published (early years) or listed in Mouse News Letter (later years).
39-1   The relationships of strains of the C57 group.
39-2   The relationships of strains of the DBA, BALB/c, A, and related strains.
39-3   Relationships of sublines within four unrelated groups of strains.
40-1   Agar gel electrophoresis of the nondialyzable material.
42-1   The approximate geographic limits of house mice (Mus) in western Europe and northwestern Africa.
42-2   Genetic distance (D) for samples of an inbred lab strain and native mice (Mus) from England and Spain.
45-1   Chromosomes of Mus musculus stained with quinacrine.
45-2   Chromosomes of Mus cervicolor stained with quinacrine.
45-3   Comparison of the G-band pattern of the chromosomes of a) M. musculus musculus, b) M. musculus molossinus, c) M. caroli, d) M. cervicolor, e) m. cookii, and f) M. booduga fulvidentris.
45-4   Chromosomes of M. dunni stained with conventional Giemsa and to show C-banding.
45-5   Karyotype of M. poschiavinus (2n=26).
45-6   Meiotic cell of a (T Rov 1-6 x M. poschiavinus)F1 stained with Giemsa.
45-7   Karyotype of (musculus x molossinus)F1 stained to show C-bands.
45-8   Meiotic cell from a (musculus x molossinus)F1 stained to show C-bands.
45-9   Metaphase of Mus musculus stained to show the concentration of 5-methylcytosine in the C-band regions.
45-10   Partial karyotype of molossinus stained to show Q-bands, Ag-stained NORs and C-bands.
45-11   Karyotype of a Chinese hamster-mouse somatic hybrid cell.
46-1   Distribution of mice trapped on Great Gull Island after release of +/tw11 males in 1956 and 1957.
47-1   Correlation between the extent of cross-reactivity of anti-H-2Dd sera on human and mice cells.
49-1   The genetic map of the H-2 complex.
49-2   Distribution of 15 inbred-derived antigens among 40 wild mice from the area of Ann Arbor, Michigan.
49-3   Method used for the production of B10.W lines.
50-1   Phylogenetic tree depicting relationships among members of the family Muridae.
50-2   Competitive radioimmunoassays for P30 proteins.
50-3   Electron micrographs of virus particles from NIH/3T3 cells infected with M. cervicolor M432 and M. musculus type B (MMTV) virus from RIII tumor cells.
50-4   Competitive radioimmunoassay for M. cervicolor M432 p24 protein.
50-5   Hybridization of 3H-labeled DNA probes prepared from each of the M. cervicolor retroviruses to M. cervicolor DNA.