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Example of a phenotype description

The following is an example of a description for the Wnt3avt mutant allele.

Homozygotes have very short tails, varying from complete absence to about half normal length. They tend to have fewer presacral vertebrae than normal, and the bodies of lumbar vertebrae often ossify from bilateral twin centers rather than from a single center. At 10 days of gestation when there is a ventral ectodermal ridge at the zone of growth of the tail tip, the ridge is much reduced in homozygous embryos. There is also a reduction in the tail gut. The neural tube in the tail bud is abnormal in the ventral region, tending to split off and round up to form accessory tubes. The primitive streak is abnormally small and fails to fill the space within the ectoderm. Other abnormalities may be consequent on the abnormal primitive streak.
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
12/09/2014
MGI 5.20
The Jackson Laboratory