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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Ewsr1
Ewing sarcoma breakpoint region 1
MGI:99960
60 phenotypes from multigenic genotypes
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Allelic Composition
Genetic Background
Annotated Term Reference
Col1a1tm1(tetO-EWSR1/ATF1)Yasu/Col1a1+
Gt(ROSA)26Sortm1(rtTA*M2)Jae/Gt(ROSA)26Sor+
involves: 129S4/SvJae * C57BL/6
decreased fibroblast proliferation J:194505
increased sarcoma incidence J:194505
premature death J:194505
tumor regression J:194505
Col1a1tm1(tetO-EWSR1/ATF1)Yasu/Col1a1+
Gt(ROSA)26Sortm1(rtTA*M2)Jae/Gt(ROSA)26Sor+
Tg(CAG-cat-lacZ)11Miya/0
H2afvTg(Wnt1-cre)11Rth/0
involves: 129S4/SvJae * C57BL/6 * CBA/J * DBA/2
increased sarcoma incidence J:194505
Col1a1tm1(tetO-EWSR1/ATF1)Yasu/Col1a1+
Gt(ROSA)26Sortm1(rtTA*M2)Jae/Gt(ROSA)26Sortm1(EYFP)Cos
Tg(Mpz-cre)94Imeg/0
involves: 129S4/SvJae * 129X1/SvJ * C57BL/6
increased sarcoma incidence J:194505
Ewsr1tm1Sblee/Ewsr1+
Tg(CAG-cre/Esr1*)5Amc/0
involves: 129S6/SvEvTac * C57BL/6 * CBA
no abnormal phenotype detected J:156860
Ewsr1tm1Sblee/Ewsr1tm1Sblee
involves: 129S6/SvEvTac * Black Swiss
abnormal cell nucleus morphology J:122058
abnormal male meiosis J:122058
abnormal ovary morphology J:122058
abnormal spermatid morphology J:122058
abnormal testis morphology J:122058
absent corpus luteum J:122058
absent ovarian follicles J:122058
absent subcutaneous adipose tissue J:122058
decreased body weight J:122058
decreased bone mineral density J:122058
decreased double-positive T cell number J:122058
decreased immature B cell number J:122058
decreased leukocyte cell number J:122058
decreased mature B cell number J:122058
decreased pre-B cell number J:122058
early cellular replicative senescence J:122058
female infertility J:122058
increased mortality induced by gamma-irradiation J:122058
kyphosis J:122058
male infertility J:122058
muscular atrophy J:122058
postnatal growth retardation J:122058
preweaning lethality, incomplete penetrance J:122058
small ovary J:122058
small testis J:122058
spleen hypoplasia J:122058
thymus hypoplasia J:122058
Ewsr1tm2(FLI1*)Sblee/Ewsr1+
Tg(CAG-cre/Esr1*)5Amc/0
involves: 129S6/SvEvTac * C57BL/6 * CBA
increased fibroblast apoptosis J:156860
increased renal tubule apoptosis J:156860
premature death J:156860
Gt(ROSA)26Sortm1(cre/ERT)Nat/Gt(ROSA)26Sortm4(EWSR1/ATF1)Mrc
involves: 129S1/Sv * 129X1/SvJ * C57BL/6
decreased litter size J:194308
increased sarcoma incidence J:217462
increased tumor incidence J:194308
increased tumor latency J:194308
postnatal growth retardation J:194308
premature death J:194308
Gt(ROSA)26Sortm1(EWSR1/FLI1)Sbk/Gt(ROSA)26Sor+
Tg(Mx1-cre)1Cgn/?
involves: 129S1/Sv * C57BL/6 * CBA
abnormal blood cell morphology/development J:129039
abnormal lymph node B cell domain morphology J:129039
abnormal myelopoiesis J:129039
anemia J:129039
decreased erythrocyte cell number J:129039
decreased hematocrit J:129039
enlarged liver J:129039
enlarged spleen J:129039
increased leukemia incidence J:129039
increased leukocyte cell number J:129039
increased spleen red pulp amount J:129039
premature death J:129039
thrombocytosis J:129039
Gt(ROSA)26Sortm4(EWSR1/ATF1)Mrc/Gt(ROSA)26Sor+
involves: C57BL/6
abnormal tumor latency J:194308
abnormal tumor morphology J:194308
increased incidence of tumors by chemical induction J:194308
increased tumor growth/size J:194308
Gt(ROSA)26Sortm4(EWSR1/ATF1)Mrc/Gt(ROSA)26Sor+
H2afvTg(Wnt1-cre)11Rth/?
involves: C57BL/6J * CBA/J
embryonic lethality, complete penetrance J:194308
Gt(ROSA)26Sortm4(EWSR1/ATF1)Mrc/Gt(ROSA)26Sor+
Tg(Tek-cre)1Ywa/?
involves: C57BL/6 * SJL
embryonic lethality, complete penetrance J:194308
Gt(ROSA)26Sortm4(EWSR1/ATF1)Mrc/Gt(ROSA)26Sor+
Tg(Prrx1-cre)1Cjt/?
involves: C57BL/6 * SJL
abnormal limb morphology J:194308
lethality throughout fetal growth and development, complete penetrance J:194308
Gt(ROSA)26Sortm4(EWSR1/ATF1)Mrc/Gt(ROSA)26Sor+
Pax7tm1(cre)Mrc/Pax7+
involves: 129S1/Sv * 129X1/SvJ * C57BL/6
abnormal craniofacial morphology J:194308
lethality throughout fetal growth and development, complete penetrance J:194308
Gt(ROSA)26Sortm4(EWSR1/ATF1)Mrc/Gt(ROSA)26Sor+
Pax3tm1(cre)Joe/Pax3+
involves: C57BL/6
embryonic lethality, complete penetrance J:194308
Gt(ROSA)26Sortm4(EWSR1/ATF1)Mrc/Gt(ROSA)26Sor+
Myf5tm1(cre)Mrc/Myf5+
involves: 129S1/Sv * 129X1/SvJ * C57BL/6
decreased body size J:194308
myopathy J:194308
premature death J:194308
Gt(ROSA)26Sortm4(EWSR1/ATF1)Mrc/Gt(ROSA)26Sor+
Bmi1tm1(cre/ERT)Mrc/Bmi1+
involves: 129S1/Sv * 129X1/SvJ * C57BL/6
increased tumor incidence J:194308
Gt(ROSA)26Sortm4(EWSR1/ATF1)Mrc/Gt(ROSA)26Sor+
Tg(Prrx1-cre/ERT2)1Mlgn/?
involves: C57BL/6
increased tumor incidence J:194308
myopathy J:194308
Gt(ROSA)26Sortm4(EWSR1/ATF1)Mrc/Gt(ROSA)26Sor+
Pax7tm1(cre/ERT2)Gaka/Pax7+
involves: 129S6/SvEvTac * C57BL/6
myopathy J:194308
normal neoplasm J:194308

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
04/16/2019
MGI 6.13
The Jackson Laboratory