Lama2 Phenotype Annotations - Multigenic Genotypes

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Lama2
laminin, alpha 2
MGI:99912

30 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Bax^tm1Sjk/Bax^tm1Sjk Lama2^tm1Eeng/Lama2^tm1Eeng B6.129-Bax^tm1Sjk Lama2^tm1Eeng	abnormal postnatal growth/weight/body size	J:94431
	abnormal skeletal muscle fiber morphology	J:94431
	normal behavior/neurological phenotype	J:94431
	decreased body size	J:94431
	decreased body weight	J:94431
	extended life span	J:94431
	impaired skeletal muscle regeneration	J:94431
	increased skeletal muscle mass	J:94431
C3^tm1Hrc/C3^tm1Hrc Lama2^dy/Lama2^dy either: (involves: 129S2/SvPas * 129P1/ReJ) or (involves: 129X1/SvJ * 129P1/ReJ)	abnormal physical strength	J:102959
	abnormal skeletal muscle morphology	J:102959
	decreased IgM level	J:102959
	dystrophic muscle	J:102959
	extended life span	J:102959
	increased body weight	J:102959
	increased IgG level	J:102959
	increased IgM level	J:102959
	skeletal muscle interstitial fibrosis	J:102959
Lama2^dy-2J/Lama2^dy-2J Lama4^tm1Ktry/Lama4^tm1Ktry involves: 129X1/SvJ * C57BL/6 * WK/ReJ	abnormal basal lamina morphology	J:98086
	abnormal motor capabilities/coordination/movement	J:98086
	abnormal myelination	J:98086
	decreased body size	J:98086
	decreased Schwann cell number	J:98086
	limb grasping	J:98086
	normal nervous system phenotype	J:98086
	postnatal lethality, complete penetrance	J:98086
	tremors	J:98086
Lama2^dy-2J/Lama2^dy-2J Lama4^tm1Ktry/Lama4^tm1Ktry Tg(ACTB-Lama5)1Jhm/0 involves: 129X1/SvJ * C57BL/6 * WK/ReJ	abnormal basal lamina morphology	J:98086
	normal behavior/neurological phenotype	J:98086
	normal nervous system phenotype	J:98086
Lama2^dy/Lama2^dy Lama4^tm1Ktry/Lama4^tm1Ktry involves: 129P1/ReJ * 129X1/SvJ	abnormal rostral migratory stream morphology	J:120076
Lama2^tm1Eeng/Lama2^tm1Eeng Smdt1^{tm1c(EUCOMM)Wtsi}/Smdt1^{tm1c(EUCOMM)Wtsi} Tg(Ckmm-cre)5Khn/0 involves: 129S1/Sv * 129S4/SvJae * C57BL/6N * FVB	abnormal mitochondrial physiology	J:287405
	decreased grip strength	J:287405
	premature death	J:287405
Lama2^tm1Eeng/Lama2^tm1Eeng Tg(Myod1-BCL2)1Jbm/? B6.Cg-Lama2^tm1Eeng Tg(Myod1-BCL2)1Jbm	abnormal postnatal growth/weight/body size	J:94431
	extended life span	J:94431
Lama2^tm1Stk/Lama2^tm1Stk Lama4^tm1Ktry/Lama4^tm1Ktry involves: 129P2/OlaHsd * 129X1/SvJ	abnormal axon radial sorting	J:98086
	decreased Schwann cell number	J:98086
	postnatal lethality, complete penetrance	J:98086
Lama2^tm1Stk/Lama2^tm1Stk Tg(CAG-Lama1)12Mdur/0 involves: 129P2/OlaHsd * C57BL/6 * CBA	normal reproductive system phenotype	J:100711

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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