Lama3 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Lama3
laminin, alpha 3
MGI:99909

28 phenotypes from 3 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Lama3^tm1.1Grsb/Lama3^tm1.1Grsb involves: C57BL/6	abnormal alveolar macrophage physiology	J:235712
	abnormal chemokine level	J:235712
	abnormal lung hysteresivity	J:235712
	abnormal protein level	J:235712
	abnormal susceptibility to injury induced morbidity/mortality	J:235712
	abnormal tumor necrosis factor level	J:235712
	decreased airway resistance	J:235712
	decreased susceptibility to injury	J:235712
	increased alveolar macrophage number	J:235712
	increased collagen level	J:235712
	lung inflammation	J:235712
Lama3^tm1Arte/Lama3^tm1Arte Tg(KRT14-cre/ERT)20Efu/0 involves: C57BL/6 * CD-1	abnormal hair follicle orientation	J:240054
	abnormal nail morphology	J:240054
	bleb	J:240054
	blistering	J:240054
	decreased body size	J:240054
	dermal-epidermal separation	J:240054
	increased collagen level	J:240054
	skin fibrosis	J:240054
	skin inflammation	J:240054
	thick skin	J:240054
Lama3^tm1Crt/Lama3^tm1Crt involves: 129 * C57BL/6J	abnormal ameloblast morphology	J:55865
	abnormal enamel morphology	J:55865
	abnormal epidermal layer morphology	J:55865
	abnormal epidermis stratum basale morphology	J:55865
	blistering	J:55865
	decreased body weight	J:55865
	disorganized suprabasal layer	J:55865
	postnatal lethality, complete penetrance	J:55865
	small stomach	J:55865

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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