Kdm5c Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Kdm5c
lysine demethylase 5C
MGI:99781

19 phenotypes from 4 alleles in 4 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Kdm5c^{Gt(E008C01)Wrst}/Y Not Specified	no abnormal phenotype detected	J:160967
Kdm5c^{Gt(P026G11)Wrst}/Y chimera involves: 129S6/SvEvTac * C57BL/6	abnormal developmental patterning	J:160967
	abnormal heart morphology	J:160967
Kdm5c^tm1.2Yshi/Y involves: 129 * 129S1/SvImJ * C57BL/6J	abnormal dendritic mushroom spine morphology	J:262206
	abnormal dendritic spine morphology	J:262206
	abnormal impulsive behavior control	J:262206
	abnormal pyramidal neuron dendrite morphology	J:262206
	abnormal social investigation	J:262206
	decreased anxiety-related response	J:262206
	decreased body size	J:262206
	decreased body weight	J:262206
	decreased dendritic spine density	J:262206
	impaired contextual conditioning behavior	J:262206
	impaired cued conditioning behavior	J:262206
	impaired spatial learning	J:262206
	increased aggression towards mice	J:262206
	increased circulating testosterone level	J:262206
	normal reproductive system phenotype	J:262206
Kdm5c^{tm1d(EUCOMM)Hmgu}/Kdm5c^{tm1d(EUCOMM)Hmgu} C57BL/6N-Kdm5c^{tm1d(EUCOMM)Hmgu}/Ics	preweaning lethality, complete penetrance	J:211773

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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