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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Smarca2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
MGI:99603
20 phenotypes from multigenic genotypes
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Allelic Composition
Genetic Background
Annotated Term Reference
Smarca2tm1Mya/Smarca2+
Smarca4tm1.2Pcn/Smarca4tm1.1Pcn
Tg(Myh11-cre,-EGFP)2Mik/0
involves: 129S2/SvPas * C57BL/6 * DBA/2
abnormal small intestine morphology J:172661
decreased colon length J:172661
decreased small intestine length J:172661
enlarged cecum J:172661
megacolon J:172661
Smarca2tm1Mya/Smarca2tm1Mya
Smarca4tm1.1Pcn/Smarca4+
involves: 129S2/SvPas * C57BL/6 * DBA/2
abnormal muscle physiology J:172661
normal digestive/alimentary phenotype J:172661
Smarca2tm1Mya/Smarca2tm1Mya
Smarca4tm1.2Pcn/Smarca4tm1.1Pcn
Tg(Myh11-cre,-EGFP)2Mik/0
involves: 129S2/SvPas * C57BL/6 * DBA/2
abnormal digestive system morphology J:172661
abnormal intestinal smooth muscle morphology J:172661
abnormal intestine morphology J:172661
abnormal muscle physiology J:172661
abnormal small intestine morphology J:172661
abnormal urinary bladder morphology J:172661
impaired smooth muscle contractility J:172661
postnatal lethality, complete penetrance J:172661
Smarca2tm1Mya/Smarca2tm1Mya
Smarca4tm1.2Pcn/Smarca4tm1.2Pcn
Tg(KRT14-cre/ERT2)1Ipc/?
involves: 129S2/SvPas
abnormal epidermis stratum corneum morphology J:101729
abnormal epidermis stratum granulosum morphology J:101729
abnormal skin morphology J:101729
enlarged spinous cells J:101729
impaired skin barrier function J:101729
Smarca2tm1Mya/Smarca2tm1Mya
Smarca4tm1Mag/Smarca4+
involves: 129S/Sv * 129S2/SvPas * C57BL/6J * CD-1
increased hemangiosarcoma incidence J:132091
increased mammary gland tumor incidence J:132091

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
08/13/2019
MGI 6.14
The Jackson Laboratory