60 phenotypes from 7 alleles in 9 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
S1pr2stdf/S1pr2stdf involves: C57BL/6Brd * C57BL/6N	abnormal organ of Corti morphology	J:240361
	abnormal stria vascularis vasculature morphology	J:240361
	abnormal strial marginal cell morphology	J:240361
	cochlear outer hair cell degeneration	J:240361
	decreased endocochlear potential	J:240361
	impaired hearing	J:240361
	increased or absent threshold for auditory brainstem response	J:240361
	stria vascularis degeneration	J:240361
S1pr2tm1.1Toka/S1pr2tm1.1Toka involves: C57BL/6J * C57BL/6N	premature death	J:214445
S1pr2tm1Ajml/S1pr2tm1Ajml 129S5/SvEvBrd-S1pr2tm1Ajml	increased B cell derived lymphoma incidence	J:154439
S1pr2tm1Ajml/S1pr2tm1Ajml either: (involves: 129S5/SvEvBrd) or (involves: 129S5/SvEvBrd * C57BL/6)	abnormal Rosenthal canal morphology	J:112371
	abnormal tectorial membrane morphology	J:112371
	abnormal vestibular system physiology	J:112371
	cochlear outer hair cell degeneration	J:112371, J:231927
	deafness	J:112371, J:231927
	decreased otolith number	J:112371, J:231927
	detached Reissner membrane	J:112371
	head tilt	J:112371
	impaired swimming	J:112371
	increased or absent threshold for auditory brainstem response	J:112371
	organ of Corti degeneration	J:112371
	otosclerosis	J:112371
	premature death	J:112371
	seizures	J:112371
	small scala media	J:112371
	thin stria vascularis	J:112371, J:231927
	vestibular saccular degeneration	J:112371
S1pr2tm1Ajml/S1pr2tm1Ajml involves: 129S5/SvEvBrd * C57BL/6	abnormal action potential	J:73957
	abnormal brain wave pattern	J:73957
	abnormal CNS synaptic transmission	J:73957
	abnormal excitatory postsynaptic currents	J:73957
	abnormal nervous system electrophysiology	J:73957
	abnormal spleen marginal zone morphology	J:154439
	increased B cell derived lymphoma incidence	J:154439
	increased excitatory postsynaptic current amplitude	J:73957
	increased excitatory postsynaptic current frequency	J:73957
	increased germinal center B cell number	J:154439
	increased lung tumor incidence	J:154439
	increased spleen germinal center number	J:154439
	increased spleen germinal center size	J:154439
	increased T cell number	J:154439
	seizures	J:73957
	tonic-clonic seizures	J:73957
S1pr2tm1Jch/S1pr2tm1Jch involves: 129S1/Sv * 129X1/SvJ * C57BL/6N	absent startle reflex	J:118369
	decreased litter size	J:77809
S1pr2tm1Rlp/S1pr2tm1Rlp involves: 129S6/SvEvTac * C57BL/6	abnormal spleen germinal center morphology	J:174313
	abnormal stria vascularis morphology	J:121165
	abnormal stria vascularis vasculature morphology	J:121165
	abnormal strial basal cell morphology	J:121165
	abnormal strial intermediate cell morphology	J:121165
	abnormal strial marginal cell morphology	J:121165
	abnormal vestibular labyrinth morphology	J:121165
	absent distortion product otoacoustic emissions	J:121165
	normal cardiovascular system phenotype	J:106055
	cochlear ganglion degeneration	J:121165
	cochlear hair cell degeneration	J:121165
	deafness	J:121165
	decreased B cell apoptosis	J:174313
	decreased otolith number	J:121165
	enlarged otoliths	J:121165
	head tilt	J:121165
	increased B cell number	J:174313
	increased B cell proliferation	J:174313
	increased germinal center B cell number	J:174313
	increased or absent threshold for auditory brainstem response	J:121165
	increased T cell number	J:174313
	organ of Corti degeneration	J:121165
S1pr2tm1Ytak/S1pr2tm1Ytak involves: 129P2/OlaHsd * C57BL/6	abnormal tumor morphology	J:168060
	abnormal tumor vascularization	J:168060
	increased angiogenesis	J:168060
	increased lung endothelial cell migration	J:168060
	increased tumor growth/size	J:168060
	postnatal lethality, incomplete penetrance	J:168060
	seizures	J:168060
S1pr2tm2Ytak/S1pr2tm2Ytak B6.129P2-S1pr2tm2Ytak	normal nervous system phenotype	J:168060