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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Pde4b
phosphodiesterase 4B, cAMP specific
MGI:99557
24 phenotypes from 3 alleles in 7 genetic backgrounds
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Allelic Composition
Genetic Background
Annotated Term Reference
Pde4benu1H/Pde4benu1H
B6.C(C3H)-Pde4benu1H
abnormal CNS synaptic transmission J:223217
abnormal learning/memory/conditioning J:223217
abnormal neuron differentiation J:223217
abnormal object recognition memory J:223217
normal behavior/neurological phenotype J:223217
decreased anxiety-related response J:223217
decreased synaptic depression J:223217
enhanced learning J:223217
enhanced long-term potentiation J:223217
enhanced spatial working memory J:223217
impaired cued conditioning behavior J:223217
increased exploration in new environment J:223217
increased post-tetanic potentiation J:223217
increased vertical activity J:223217
normal nervous system phenotype J:223217
normal taste/olfaction phenotype J:223217
Pde4benu1H/Pde4benu1H
Tg(Thy1-EGFP)#Jrs/0
involves: BALB/cAnN * C3H/HeH * C57BL/6 * CBA
increased dendritic spine density J:223217
Pde4btm1Dgen/Pde4btm1Dgen
involves: 129P2/OlaHsd * C57BL/6J
abnormal spinal cord morphology J:82809
brain vacuoles J:82809
Pde4btm1Mct/Pde4btm1Mct
B6N.129P2-Pde4btm1Mct/Mmucd
normal behavior/neurological phenotype J:304450
Pde4btm1Mct/Pde4btm1Mct
involves: 129P2/OlaHsd
normal cardiovascular system phenotype J:96125
Pde4btm1Mct/Pde4btm1Mct
involves: 129P2/OlaHsd * C57BL/6
decreased susceptibility to induced morbidity/mortality J:106828
decreased tumor necrosis factor secretion J:106828
impaired neutrophil chemotaxis J:94853
impaired neutrophil recruitment J:94853
Pde4btm1Mct/Pde4btm1Mct
involves: 129X1/SvJ * C57BL/6
decreased tumor necrosis factor secretion J:76862

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/09/2024
MGI 6.23
The Jackson Laboratory